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MSK Biweekly 2 > Balczon- Connective Tissue > Flashcards

Balczon- Connective Tissue Flashcards

1
Q

provides support and is derived from embryonic mesenchyme

A

connective tissue

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2
Q

part of ECM that is composed of glycosaminoglycans and proteoglycans; highly hydrated

A

ground substance

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3
Q

part of ECM composed of collagen and elastin

A

fibrous proteins

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4
Q

provides tensile strength; reticular fibers

A

collagen

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5
Q

provides resiliency, resists stretching

A

elastin

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6
Q

extracellular “glue” that holds CT together (fibronectin and laminin)

A

adhesive glycoproteins

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7
Q

cells that produce and secrete extracellular matrix

A

Fibroblasts

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8
Q

cells for energy and fat storage

A

adipocytes

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9
Q

contains fibroblasts, adipocytes, and immune cells

A

CT cells

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10
Q

what kind of CT

A

dense irregular CT

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11
Q

what kind of CT

A

dense regular CT

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12
Q

what kind of CT

A

loose CT

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13
Q

what kind of CT

A

loose CT

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14
Q

what kind of CT; and what are the arrows pointing to

A

loose CT
L arrows: collagen fibers
R arrows: plasma cells

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15
Q

what are the arrows pointing to

A

L arrows: elastin bundles/fibers
R arrows: adipose tissue

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16
Q

LUNG: what is the yellow and what is the purple

A

yellow: collagen and smooth m
purple: elastin

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17
Q

PAS stain; spleen
arrows pointing to?

A

reticular fibers
top middle: macrophage

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18
Q

this shows reticular fibers where and what stain

A

lymph node
siliver stain

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19
Q
A

hyaline cartilage

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20
Q
A

chondrocytes in lacunae

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21
Q
A

elastic cartilage

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22
Q

arrows point to

A

L arrows: chondrocytes in lacunae
R arrows: elastin

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23
Q
A

fibrocartilage

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24
Q

derived from mesenchyme; complex of cells and ECM

A

connective tissue

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25
Q

provides the physical and functional properties of connective tissue

A

extracellular matrix

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26
Q

composed of ground substance, fibrous proteins, and adhesive glycoproteins

A

ECM of connective tissue

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27
Q

_____ provides the physical properties of connective tissue; by varying the organization and composition of _______ you can create a completely different functional type of CT

A

ECM (extracellular matrix)

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28
Q

“gel-like”; resists compressive forces

A

ground substance of ECM

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29
Q

2 molecules that make up ground substance

A

glycosaminoglycans
proteoglycans

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30
Q

creates an aqueous cellular environment of ground substance

A

glycosaminoglycans

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31
Q

proteins that have a lot of glycosaminoglycans attached to it

A

proteoglycans

32
Q

an aqueous gel that allows diffusion of nutrients and wastes

A

ECM

33
Q

type of pressure produced by ECM that allow tissues to resist compressive forces

A

Turgor Pressure

34
Q

provides tensile strength to body and allows resistance to shearing forces

A

collagen

35
Q

most abundant protein in body; main type is type I

A

collagen

36
Q

cells that produce collagen

A

fibroblast

37
Q

steps in collagen synthesis:

A
  1. produced in fibroblasts and procollagen exits
  2. Pro is cleaved forming tropocollagen
  3. Pro/Lys hydroxylation and crosslink forming collagen fibrils
  4. collagen fibers formed from crosslinking collagen fibrils
38
Q

stain used to see fibrosis (overproduction of collagen)

A

trichrome

39
Q

type of collagen made up of cartilage

A

type II

40
Q

type of collagen made up by reticular fibers

A

type III

41
Q

type of collagen that makes up basement membrane/basal lamina

A

type IV

42
Q

forms internal skeleton of organs

A

type III collagen(reticular fibers)

43
Q

assembles into sheets and forms basement membrane

A

type IV collagen

44
Q

provides resiliency and allows resistance to stretching forces

A

elastin

45
Q

present in tissues that need to expand and contract

A

elastin

46
Q

differences b/t elastin and collagen synthesis

A

different modified AA’s
elastin requires scaffold protein (fibrillin)

47
Q

special stain for elastin

A

Aldehyde Fuchsin

48
Q

________ w/ their 3 binding domains crosslink entire network of cells, collagen, and glycosaminoglycans together

A

adhesive glycoproteins

49
Q

fibronectin and laminin are examples of what

A

adhesive glycoproteins

50
Q

fibroblasts, glorified fibroblasts, macrophages, plasma cells, mast cells, adipocytes

A

resident cells of CT

51
Q

WBC’s that leave blood to help fight infection are what kind of cells in CT

A

transient cells

52
Q

lots of collagen fibers; parallel arrangement

A

dense CT

53
Q

parallel arrangement of collagen that allows resistance to forces applied in 1 direction (tendons and ligaments)

A

dense regular CT

54
Q

haphazard array of collagen; resistance to forces applied in multiple directions (dermis)

A

dense irregular CT

55
Q

very few collagen fibers

A

loose CT

56
Q

skeletal support, protection/defense, transport, and storage

A

functions of CT

57
Q

specialized for storage of excess calories in the form of triglycerides

A

adipose tissue

58
Q

cell that makes up adipose tissue

A

adipocyte

59
Q

type of adipocyte where all the triglycerides are contained in a single lipid droplet—white fat

A

unilocular

60
Q

all of the triglycerides are stored in multiple lipid droplets—brown fat

A

multilocular

61
Q

specialized function of this is heat production for newborns who can’t shiver yet

A

brown fat

62
Q

storage, temperature regulation, protection, endocrine

A

functions of adipose tissue

63
Q

has weight bearing capacities and rapid growth

A

cartilage

64
Q

3 types of cartilage

A

hyaline
elastic
fibrocartilage

65
Q

contains ground substance that makes it slippery and produces turgor pressure

A

ECM of hyaline and elastic cartilage

66
Q

fibers that make up ECM of cartilage

A

type II collagen fibers

67
Q

produces specialized ECM in cartilage

A

chondrocyte

68
Q

live within lacunae

A

chondrocytes

69
Q

CT capsule of cartilage composed of this

A

perichondrium

70
Q

part of cartilage composed of type I collagen

A

perichondrium

71
Q

difference between hyaline and elastic cartilage

A

elastic contains elastin in matrix of cartilage

72
Q

cartilage between ribs

A

hyaline

73
Q

cartilage in ears

A

elastic

74
Q

difference of hyaline, elastic, and fibrocartilage

A

fibrocartilage has type I collagen

75
Q

cartilage in intervertebral discs that allows resistance to shearing

A

fibrocartilage

76
Q

skeletal support, protection, scaffold upon which bone is formed

A

functions of cartilage

MSK Biweekly 2 (6 decks)

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