Balczon- Connective Tissue Flashcards

1
Q

provides support and is derived from embryonic mesenchyme

A

connective tissue

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2
Q

part of ECM that is composed of glycosaminoglycans and proteoglycans; highly hydrated

A

ground substance

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3
Q

part of ECM composed of collagen and elastin

A

fibrous proteins

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4
Q

provides tensile strength; reticular fibers

A

collagen

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5
Q

provides resiliency, resists stretching

A

elastin

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6
Q

extracellular “glue” that holds CT together (fibronectin and laminin)

A

adhesive glycoproteins

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7
Q

cells that produce and secrete extracellular matrix

A

Fibroblasts

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8
Q

cells for energy and fat storage

A

adipocytes

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9
Q

contains fibroblasts, adipocytes, and immune cells

A

CT cells

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10
Q

what kind of CT

A

dense irregular CT

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11
Q

what kind of CT

A

dense regular CT

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12
Q

what kind of CT

A

loose CT

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13
Q

what kind of CT

A

loose CT

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14
Q

what kind of CT; and what are the arrows pointing to

A

loose CT
L arrows: collagen fibers
R arrows: plasma cells

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15
Q

what are the arrows pointing to

A

L arrows: elastin bundles/fibers
R arrows: adipose tissue

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16
Q

LUNG: what is the yellow and what is the purple

A

yellow: collagen and smooth m
purple: elastin

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17
Q

PAS stain; spleen
arrows pointing to?

A

reticular fibers
top middle: macrophage

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18
Q

this shows reticular fibers where and what stain

A

lymph node
siliver stain

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19
Q
A

hyaline cartilage

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20
Q
A

chondrocytes in lacunae

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21
Q
A

elastic cartilage

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22
Q

arrows point to

A

L arrows: chondrocytes in lacunae
R arrows: elastin

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23
Q
A

fibrocartilage

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24
Q

derived from mesenchyme; complex of cells and ECM

A

connective tissue

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25
provides the physical and functional properties of connective tissue
extracellular matrix
26
composed of ground substance, fibrous proteins, and adhesive glycoproteins
ECM of connective tissue
27
_____ provides the physical properties of connective tissue; by varying the organization and composition of _______ you can create a completely different functional type of CT
ECM (extracellular matrix)
28
"gel-like"; resists compressive forces
ground substance of ECM
29
2 molecules that make up ground substance
glycosaminoglycans proteoglycans
30
creates an aqueous cellular environment of ground substance
glycosaminoglycans
31
proteins that have a lot of glycosaminoglycans attached to it
proteoglycans
32
an aqueous gel that allows diffusion of nutrients and wastes
ECM
33
type of pressure produced by ECM that allow tissues to resist compressive forces
Turgor Pressure
34
provides tensile strength to body and allows resistance to shearing forces
collagen
35
most abundant protein in body; main type is type I
collagen
36
cells that produce collagen
fibroblast
37
steps in collagen synthesis:
1. produced in fibroblasts and procollagen exits 2. Pro is cleaved forming tropocollagen 3. Pro/Lys hydroxylation and crosslink forming collagen fibrils 4. collagen fibers formed from crosslinking collagen fibrils
38
stain used to see fibrosis (overproduction of collagen)
trichrome
39
type of collagen made up of cartilage
type II
40
type of collagen made up by reticular fibers
type III
41
type of collagen that makes up basement membrane/basal lamina
type IV
42
forms internal skeleton of organs
type III collagen(reticular fibers)
43
assembles into sheets and forms basement membrane
type IV collagen
44
provides resiliency and allows resistance to stretching forces
elastin
45
present in tissues that need to expand and contract
elastin
46
differences b/t elastin and collagen synthesis
different modified AA's elastin requires scaffold protein (fibrillin)
47
special stain for elastin
Aldehyde Fuchsin
48
________ w/ their 3 binding domains crosslink entire network of cells, collagen, and glycosaminoglycans together
adhesive glycoproteins
49
fibronectin and laminin are examples of what
adhesive glycoproteins
50
fibroblasts, glorified fibroblasts, macrophages, plasma cells, mast cells, adipocytes
resident cells of CT
51
WBC's that leave blood to help fight infection are what kind of cells in CT
transient cells
52
lots of collagen fibers; parallel arrangement
dense CT
53
parallel arrangement of collagen that allows resistance to forces applied in 1 direction (tendons and ligaments)
dense regular CT
54
haphazard array of collagen; resistance to forces applied in multiple directions (dermis)
dense irregular CT
55
very few collagen fibers
loose CT
56
skeletal support, protection/defense, transport, and storage
functions of CT
57
specialized for storage of excess calories in the form of triglycerides
adipose tissue
58
cell that makes up adipose tissue
adipocyte
59
type of adipocyte where all the triglycerides are contained in a single lipid droplet---white fat
unilocular
60
all of the triglycerides are stored in multiple lipid droplets---brown fat
multilocular
61
specialized function of this is heat production for newborns who can't shiver yet
brown fat
62
storage, temperature regulation, protection, endocrine
functions of adipose tissue
63
has weight bearing capacities and rapid growth
cartilage
64
3 types of cartilage
hyaline elastic fibrocartilage
65
contains ground substance that makes it slippery and produces turgor pressure
ECM of hyaline and elastic cartilage
66
fibers that make up ECM of cartilage
type II collagen fibers
67
produces specialized ECM in cartilage
chondrocyte
68
live within lacunae
chondrocytes
69
CT capsule of cartilage composed of this
perichondrium
70
part of cartilage composed of type I collagen
perichondrium
71
difference between hyaline and elastic cartilage
elastic contains elastin in matrix of cartilage
72
cartilage between ribs
hyaline
73
cartilage in ears
elastic
74
difference of hyaline, elastic, and fibrocartilage
fibrocartilage has type I collagen
75
cartilage in intervertebral discs that allows resistance to shearing
fibrocartilage
76
skeletal support, protection, scaffold upon which bone is formed
functions of cartilage