Bactira Flashcards
How can differentere between staph and strep?
And between staph family
By catalas test ➡️staph + and strep -
By coagulas test ➡️staph .auras + another ( epidermis ➕saprophyticus)
genas staphylococcus ؟
gram+
Cocci in cluster
Non motail
Common Tybe of staphylococcus?
S.auras
What is distinguished feature s. auras?
Small
Golden yellow colony in blood agar and farmantation mentanol in mentanol salt agar
B hymolatic positiv ➡️all Tybe of staph is negative
What is reservoir and transition s.auras ?
Reservoir:nasal mucosa and skin it well be in normal flora in (25-30% populations carriers) النسبه للميكوزا
Transetion: hand +sneezing+surgical wounds +contamination foods
What is predisposing factor for infection in s.auras?
Surgery and Wound
Foragen body (like tampons ,sutures ,backing)
Sever neutropena اقل من 500
IV abuse
Chronic granulomatous
Cystic fibrosis
What is bathogenesis s.auras?
Prioren A ➡️bind Fc components of IgG. (phagocytosis)بتالي بمنع الماكروفاج من الارتباط اذا منع عمليه
Enterotoxin➡️food bossing by fast acting and ❗️heat stableهرن مهم كلمه
TSST1➡️Supraantagen(cytokines Strom)
Coagulates ➡️clot بتالي بعمل Fibrinogen to Fibern هاد بحول
Cytolytic toxine (a toxin)➡️ Pore forming Toxi like pVL(panton valintin leucocidan) بعمل على زياده الشرايسه متلا في MRSA
Exfolitine ➡️skin exfoltine toxine بعمل Scalded skin Syndrom and impetigo and bullos الفقاعات
What is knows about TSST1 ?
*superantigen
*non specific ➡️to pinding of toxin to receptor triggers ➡️excessive immune response
What is mechanism staphylococcus enterotoxin?
Vomiting➡️by directly effects in intestinal epithelium that stumulation of vages nerve that transition signal to the vomiting center in the brain.
Diarrhoea➡️by distrub activity in large intestines (water can’t absorption in large intestine).
What is distinctive characteristic of s. auras about anthor bacteria Tybe ?
Heat stable ➡️all Tybe Bactria is heat boil يعني كل انواع البكتيريا بتموت بالحراره ما عدا هاد النوع بتحمل الحراره
S. auras that case many diseas like ?
Slide 13+14
S.auras most common case to ?
*Acut indocardiatis
*osteomylites ➡️and arthritis either hematogenous or traumatic cased by s.auraus in children
ERYSIPELOTHRIX Reservoir? Transmission
Manly swine الخنازير Reservoir✔️
Humans acquire the infection through occupational exposure, such as cuts & scratches (fish handlers, animal products). Transmission✔️