Bacterial, Viral, Fungal, and Parasitic Infections - ATI Chapter 56 Flashcards
______ are the micro-organisms or microbes that cause infections.
Pathogens
_____ is the ability of a pathogen to invade the host and cause disease.
Virulence
_____ is a common viral infection that erupts years after exposure to chickenpox and invades a specific nerve tract.
Herpes zoster i
_______ is the most common type of pathogen (Staphylococcus aureus, Escherichia coli, Mycobacterium tuberculosis)
bacteria
______ are organisms that use the host’s genetic machinery to reproduce (rhinovirus, HIV, hepatitis, herpes zoster, herpes simplex)
viruses
____ are molds and yeasts (Candida albicans, Aspergillus)
fungi
_____ are protein particles that have the ability to cause infections (Creutzfeldt-Jakob disease).
prions
____ are organisms that live on and often cause harm to a host organism.
parasites
Malaria and toxoplasmosis are examples of
protozoa
Worms: flatworms, roundworms are examples of
Helminths
Schistosomes are examples of
Flukes
Lice, mites, ticks are examples of
Arthropods
The infection process (________) includes the following.
chain of infection
______ of infections include bacteria, viruses, fungus, prion and parasites.
causative agent
Examples of ______ of infection include humans, animals, food, water, soil, insects, and fomites.
reservoir
Portals of exit from (means leaving) the host
respiratory tract gastrointestinal tract genitourinary tract skin/mucous membranes blood/body fluids
HIV and hepatitis B and C exit the body (portal of exit) via ______.
blood/body fluids
Herpes simplex virus and varicella exit the body (portal of exit) via ______.
skin/mucous membranes
Escherichia coli, herpes simplex virus (type 1), HIV exit the body (portal of exit) via _______.
genitourinary tract
Shigella, Salmonella enteritidis, Salmonella typhi, hepatitis A, C. diff exit the body (portal of exit) via ______.
gastrointestinal tract
Mycobacterium tuberculosis and Parainfluenza virus exit the body (portal of exit) via ______.
respiratory tract
Modes of transmissions
contact
droplet
airborne
vector-borne
Contact modes of transmission
direct physical contact
indirect contact with a vehicle of transmission
fecal-oral transmission
Person to person transmission is known as _____ contact.
direct physical
Inanimate objects, water, food, and blood are modes of transmission known as _______.
indirect contact with a vehicle of transmission
Handling food after using a restroom and failing to wash hands result in the _______.
fecal-oral transmission
_____ transmission is when large droplets travel through the air up to 3 to 6 feet (sneezing, coughing, and talking).
droplet
_____ transmission is when small droplets remain int he air and can travel extended distances depending on airflow (sneezing and coughing)
airborne
_____ transmission occurs when animals or insects as intermediaries (ticks transmit Lyme disease; mosquitoes transmit West Nile virus and malaria).
vector-borne
The portal of ______ to the host is often the same as the portal of exit.
entry
A _______ has compromised defense mechanisms (immunosuppression, breaks in skin) leave the host more susceptible to infections.
susceptible host
______ allows the body to restrict entry or immediately respond to a foreign organisms (antigen) through the activation of phagocytic cells, complement and inflammation.
nonspecific innate - native immunity
______ immunity provides temporary immunity but does not have memory of past exposures.
nonspecific innate-native
Intact skin is the body’s _____ of defense against microbial invasion.
first line
The skin, mucous membranes, secretions, enzymes, phagocytic cells, and _______ work in concert to prevent infections.
protective proteins
Phagocyic cells (neutrophils, eosinophils, macrophages), the complement system, and ______ are involved in the inflammatory response.
interferons
An ________ localizes the area of microbial invasion and prevents its spread.
inflammatory response
_______ allows the body to make antibodies in response to a foreign organism (antigen).
specific adaptive immunity
Specific adaptive immunity requires time to react to _____.
antigens
_____ immunity provides permanent immunity due to memory of past exposures.
specific adaptive
______ immunity involves B and T lymphocytes.
specific adaptive
Specific adaptive immunity produces specific ______ against specific antigens (immunoglobulins: IgA, IgD, IgE, IgG, IgM)
antibodies
The 5 immunoglobulins produced via specific adaptive immunity
IgA IgD IgE IgG IgM
Environmental Risk Factors
excessive alcohol consumption
nicotine use: smoking, smokeless tobacco
malnutrition
Medication therapy (immunosuppressive agents) Risk Factors
glucocorticosteroids
antineoplastics
Chronic disease Risk factors
Diabetes mellitus Cancer HIV, AIDS Peripheral vascular disease Chronic pulmonary disease Heart failure
Older adults are at increased risk for _______.
infection
Older adults are at increased risk for infection because of the slowed response to ______.
antibiotic therapy
Older adults are at increased risk for infection because of the slowed ______: indicators of infection are more difficult to identify, resulting in possible delays in diagnosis and treatment.
immune response
Older adults are at increased risk for infection because of the loss of _______ and thinning of the skin.
subcutaneous tissue
Older adults are at increased risk for infection because of the decreased vascularity and slowed ______.
wound healing
Older adults are at increased risk for infection because of the decreased cough and ____ reflexes.
gag
Older adults are at increased risk for infection because of the ________ such as diabetes mellitus, COPD, neurological or musculoskeletal impairments)
chronic illnesses
Older adults are at increased risk for infection because of the decreased _____ acid production.
gastric
Older adults are at increased risk for infection because of the _____ mobility.
decreased
Older adults are at increased risk for infection because of the bowel/bladder ______.
incontinence
Older adults are at increased risk for infection because of _______.
dementia
Older adults are at increased risk for infection because of the greater incidence of _____ devices (urinary catheters, feeding tubes, tracheostomies, intravenous lines)
invasive
Common indications of _____ are not always present in the older adult client. Altered mental status, agitation, or incontinence can be present instead.
infection
Expected findings with infections
chills
sore throat
fatigue and malaise
change in level of consciousness, nuchal rigidity, photophobia, headache
nausea, vomiting, anorexia, abdominal cramping and diarrhea
localized pain or discomfort
Physical assessment findings with an infection
Fever
Increased pulse and respiratory rate, decreased blood pressure
localized redness and edema
enlarged lymph nodes
dyspnea, cough, purulent sputum, and crackles in lung fields.
dysuria, urinary frequency, hematuria, and pyuria
rash, skin lesions, purulent wound drainage, and erythema
dysphagia, hyperemia, and enlarged tonsils
Lab tests for infection
white blood cell (WBC) count with differential
Erythrocyte sedimentation rate (ESR)
Immunoglobulin electrophoresis
Antibody screening tests
Antibody screening tests
Auto-antibody screening tests
Antigen tests
Stool for ova and parasites
Culture and Sensitivity
An elevated _____ is an indicator of infection (expected reference range is 5k to 10k /mm^3).
white blood cell (WBC) count
The differential with a WBC identifies specific types of WBC’s that can assist in diagnosis of the ______ of infection or the specific type of pathogen.
severity