Bacterial meningitis Flashcards
Most common pathogens < 1 month
Group B Strep
E. coli
Listeria monocytogenes
Klebsiella
Most common pathogens 1-23 months
S. pneumoniae
Neisseria meningitidis
H influenzae
E. coli
Most common pathogens 2-50 years
N. meningitidis
S. pneumoniae
Meningitis presentation: infants
poor feeding
vomiting
fever
seizures
irritability
lethargy
bulging fontanelle
Meningitis presentation: children
fever
headache
lethargy
vomiting
myalgia
photophobia
stiff neck
seizure
confusion
CSF lumbar puncture findings indicative of meningitis
WBC > 1000
Protein > 45
Glucose < 40
Empiric treatment < 1 month
Ampicillin + AG
Ampicillin + cefotaxime
(+ acyclovir if HSV suspected)
Empiric treatment 1-23 months
Vancomycin + cefotaxime or ceftriaxone
Empiric treatment 2-50 years
Vancomycin + cefotaxime or ceftriaxone
Dexamethasone in pediatric meningitis
controversial
decrease hearing loss in patients with H influenzae
always given before or with first dose of abx