Bacterial infections II-Andrews/Bolognia

Question 1

In P. Aeruginosa what causes the green color? Blue? Black?

Answer 1

Green-fluorescein, Blue-pyocyanin, Black-pyomelinin

Question 2

What causes ecthyma gangrenosum?

Answer 2

P. Aeruginosa-must assume pseudomonal sepsis

Question 3

What serotype of pseudomonas causes hot tub follicutlitis?

Answer 3

Serotype 0-11

Question 4

What is the most common cause of malakoplakia?

Answer 4

E.Coli

Question 5

What will you see in histopathology of malakoplakia?

Answer 5

Von-hansemann cells-Sheets of histiocytes with foamy eosinophilic granular cytoplasm and small, usually eccentric nuclei
Michaelis-Gutmann bodies:
Calcified, concentrically laminated intracytoplasmic basophilic bodies

Question 6

What causes ganuloma inguinale?

Answer 6

klebsiella granulomatis

Question 7

A beefy red painless ulcer/papule without regional lymphadeonpathy?

Answer 7

Granuloma inguinale

Question 8

What stains do you use to look for donovan bodies?

Answer 8

Geimsa stain/toulidine blue associated with granuloma inguinale

Question 9

What is the parasitized macrophage ddx?

Answer 9

His Pen GiRL
Histoplasmosis
Penicillium marfenii
Granuloma Inguinale 
Rhinoscleroma
Leishmaniasis

Question 10

What causes chancroid?

Answer 10

Haemophilus ducreyi

Question 11

A tender genital ulcer with unilateral painful adenitis (may suppurate “bubo”)?

Answer 11

Chancroid-haemophilus ducreyi

Question 12

How do you treat chancroid?

Answer 12

1 gm azithromycin x1

Question 13

What causes lymphogranuloma venereum?

Answer 13

Chlamydia trachomatis serotypes L1, L2, L3

Question 14

Painless herpetic ulcer that progresses to painful lymphnodes (bubo) with groove sign, then years later ano-genito-rectal syndrome?

Answer 14

lymphogranuloma venereum

Question 15

How do you treat lympogranuloma venereum?

Answer 15

Doxycycline 100 mg BID x 3 wks

Question 16

What puts a person at risk for gonococcal infection?

Answer 16

C5-C9 deficiency

Question 17

What is the gold standard for diagnosis of gonococcal disease?

Answer 17

Growth on thayer-martin agar

Question 18

In the neiseria meningitidis vaccine is effective against what serotypes?

Answer 18

A, C, Y W-135

Question 19

In typhoid fever caused by salmonella where do you see the “rose spots”?

Answer 19

2-5mm rose-colored macules or papules on the ant trunk between the nipples and umbilicus

Question 20

Hebra nose: nasal enlargement, deformity, and destruction of the nasal cartilage is caused by what?

Answer 20

klebsiella rhinoscleromatis

Question 21

What do you see in histopathology of rhinoscleroma?

Answer 21

Mikulicz’s cells (parasitized histiocytes), Russell bodies: plasma cells with eosinophillic aggregates of Immunoglobulins