Bacterial GI 1 Flashcards
Is cholera found naturally in coastal areas and estuaries?
Yes, including in the US gulf coast region
What is the reservoir of O157:H7?
Cattle
How do you treat cholera?
Fluid replacement and electrolytes
What organism usually causes traveler’s diarrhea?
Enterotoxigenic E. coli (ETEC)
How is cholera spread?
Contaminated drinking water and food
What are the 2 complications of campylobacter?
- Reiter’s syndrome in HLA-B27 peopel
2. Guillain-Barré paralytic syndrome **
What condition makes the risk of sepsis due to vibrio vulnificus very high?
Liver dysfunction/alcoholism 🍷🍻🍸
E. Coli has an O antigen and an H antigen. Which one is a seroGROUP and which one is a seroTYPE?
Serogroup: O antigen
Serotype: H antigen
Which organism causes a prodrome with fever, headache, malaise, and myalgia for 12-24 hours before the onset of diarrhea?
Campylobacter
Is h pylori infection common?
Yes
What kind of symptoms will vibrio parahaemolyticus cause?
Mild-cholera like illness
What is hemolytic uremic syndrome?
Acute renal failure with poor prognosis a few days after bloody diarrhea
What metabolite does H. Pylori produce a ton of?
Urease
This turns into ammonia and raises the pH in the stomach to help it survive. It also is the way we test for it.
Should we treat O157:H7 infections with antibiotics?
NO! Risk of HUS induction
What is the classic way to get campylobacter?
Undercooked chicken
Which two cholera serotypes cause epidemics?
O-1
O-139
Is prophylactic tetracycline treatment needed for people traveling to cholera endemic regions?
Not typically needed in people practicing normal hygiene, since the infectious dose is high
Which organism mimics appenidicits?
Campylobacter
What food products are typically associated with O157:H7?
Beef and raw milk
Undercooked hamburger is a classic infection source 🍔
Also being discovered in some vegetables like the 2006 spinach contamination
What group of people usually gets campylobacter infections?
Young, college age adults
Which organisms are associated with hemolytic uremic syndrome?
Enterohemorrhagic E. coli (EHEC) Primarily O157:H7
Shigella dysenteriae
How do you diagnose h pylori?
Histologic detection in biopsy samples + culture
CLO test- detection of urease activity in biopsy tissue by pH change
What is the chief known precipitate of guillain-barre paralytic syndrome?
Campylobacter
Does ETEC infection cause a lot of damage to intestinal mucosa?
No