Bacterial and viral infections Flashcards
What is commensal bacteria?
Bacteria present on skin but not causing disease
What are some examples of commensal bacteria?
Staphylococci MicrococciCorynebacteria Propionibacteria
Does staph aureus cause disease?
ALWAYS regarded as pathogenic May be commensal Disease associated with direct invasion of epidermis, hair follicle or production of toxin
Does streptococcal infection causes disease?
Always pathogenic Acute onset and rapid spreadSimilar disease to staph May co-infect with staph
What are the six main types of bacteria which cause clinical skin infection
staphylococcistreptococcipseudomonas aeruginosacorynebacteriummycobacterium and atypical mycobacteria spirochetes
What are different skin conditions caused by PRIMARY infection with staph. aureus?
impetigo ecthyma folliculitisfuruncle carbuncle cellulitis sycosis
What are different skin conditions caused by SECONDARY infection with staph. aureus?
infected atopic eczema infected wounds infected leg ulcers
What investigations should be carried out in suspected staph infection?
skin swabs blood cultures - normally only positive in severe sepsis due to s.aureus septicaemia
How should S.Aureus infection be treated topically?
mupirocinfuscidic acid
How should S.Aureus infection be treated orally/IV?
flucloxacillin oral/ivoral erythromycin
What disease are due to PRIMARY infection from group A streptococci?
cellulitis erysipelas perianal cellulitis necrotising fascitis
What disease are due to SECONDARY infection from group A streptococci?
infected atopic eczema leg ulcers
What disease due to Group A Streptococcal toxins?
Scarlet fever and rarely Toxic-Shock-Like-Syndrome
What diseases due to allergic hypersensitivty to Group A streptococcal toxins?
erythema nodosum erythema multiformevasculitis glomerulonephritis
How should strep be treated?
topical antibiotics not recommended oral amoxycillin/penicillin/erythromycin IV benzylpenicillin
When pseudomonas considered pathogenic?
only considered pathogenic when skin is damaged