B6.024 - Dermatopathology FLIP Prework Flashcards
epidermal inflammatory diseases
- psoriasis
- eczema
- lupus erythematosus
- lichen planus
- erythema multiforme
psoriasis
Genetic/environmental etiology
4% pop
beefy red plaques with silver scale
scalp, elbowsm knees, sacrum
allergic skin diseases: eczemas
allergic contact eczema - potent exogenous allergen
atopic eczema - endogenous predisposition
allergic contact dermatitis
caused by contact with external allergen
poison ivy
nickel
balsam of peru
neomycin
atopic eczema
lupus erythematosus
Anti DNA Antibodies (ANA)
may affect any organ, butterfly malar rash, female>male, african american >
lichen planus
pruritic
purple
polygonal
papules
Wickam striae
symmetric distrubution
30-60 yo
hepatitis C, medication, contact allergen
erythema multiforme
acute eruption
HSV, mycoplasma
young adults
target lesions
self limited
acute eruption
HSV, mycoplasma
young adults
target lesions
self limited
blistering skin diseases
- pemphigus
- pemphigoid
- dermatitis herpetiformis
pemphigus vulgaris
40-60 yo
cutaneous erosions/oral ulcers
intact blisters are rare
Painful! Not itchy
Upper trunk and head
+nikolsky
Rx CTSD, immunosuppression
pemphigus vulgaris
40-60 yo
cutaneous erosions/oral ulcers
intact blisters are rare
Painful! Not itchy
Upper trunk and head
+nikolsky
Rx CTSD, immunosuppression
bullous pemphigoid
elderly pts
tense blisters and vesicles
lower abd, thighs, FAs
10-30% involve mucosa
severe pruritis
negativec nikolky sign
rx. topical / systemic CTSDs
Elderly, tense blisters and vesicles
lower abd, thighs, FAs
severe pruritis
negative nikolsky sign
elderly, tense blisters, vesicles
severe pruritis
negative niklosky sign
dermatitis herpetiformis
broad age range
grouped pruritic papules
knees, elbows, sacrum, nape of neck, scalp
associated with HLD DQ2, DQ8 CELIACS
dapsone, gluten free diet tx
dermatitis herpetiformis
broad age range
grouped pruritic papules
knees, elbows, sacrum, nape of neck, scalp
associated with HLD DQ2, DQ8 CELIACS
dapsone, gluten free diet tx