B5.007 Prework 1 Acute Viral Gastroenteritis

Question 1

incubation of viral gastroenteritis

Answer 1

18-60 h

Question 2

duration of viral ge

Answer 2

short

Question 3

clinical symptoms of viral ge

Answer 3

"Stomach flu"
diarrhea (non blood, non inflamm)
nausea
vomiting
\+/- ab pain
\+/- fever

Question 4

complications of viral ge

Answer 4

dehydration and electrolyte loss

Question 5

treatment of viral ge

Answer 5

rehydration

Question 6

norovirus virology

Answer 6

ssRNA, nonenveloped

Question 7

seasonality of norovirus

Answer 7

winter vomiting disease

increase in severity with emergence of new strains

Question 8

norovirus transmission

Answer 8

fecal oral
highly contagious
infected food handlers
long duration of shed (up to 2 weeks)

Question 9

at risk individuals for norovirus

Answer 9

adults in close quarters
children
50% associated w long term care facilities
90% of cruise ship outbreaks

Question 10

infectivity of norovirus

Answer 10

environmentally stable
withstands freezing and heating
alcohol based hand sanitizers ineffective

Question 11

symptoms duration of norovirus

Answer 11

1-2 days

Question 12

diagnosis of norovirus

Answer 12

clinical, molecular

Question 13

rotavirus virology

Answer 13

dsRNA, nonenveloped

wheel like on EM

Question 14

rotavirus seasonality

Answer 14

late winter/ early spring

Question 15

rotavirus transmission

Answer 15

fecal oral

contaminated fomites

Question 16

at risk individuals for rotavirus

Answer 16

children (4-24 mo)
most infected by 5 years
adults usually have partial immunity and decreased severity

Question 17

infectivity of rotavirus

Answer 17

environmentally stable

Question 18

symptom duration of rotavirus

Answer 18

3-8 days

Question 19

rotavirus vaccine

Answer 19

live attenuated
85-98% protection against hospitalization
74-87% protection against illness
orally dosed to infants

Question 20

diagnosis of rotavirus

Answer 20

antigen in stool

molecular

Question 21

adenovirus virology

Answer 21

dsDNA, nonenveloped
>50 serotypes infect humans (serotypes 40/41 most associated with ge)
diverse array of symptoms

Question 22

seasonality of adenovirus

Answer 22

none

Question 23

transmission of adenovirus

Answer 23

fecal oral

Question 24

at risk individuals for adenovirus

Answer 24

children (2nd to rotavirus)

Question 25

infectivity of adenovirus

Answer 25

environmentally stable

Question 26

symptom duration of adenovirus

Answer 26

6-9 days