B5.007 Prework 1 Acute Viral Gastroenteritis Flashcards
incubation of viral gastroenteritis
18-60 h
duration of viral ge
short
clinical symptoms of viral ge
"Stomach flu" diarrhea (non blood, non inflamm) nausea vomiting \+/- ab pain \+/- fever
complications of viral ge
dehydration and electrolyte loss
treatment of viral ge
rehydration
norovirus virology
ssRNA, nonenveloped
seasonality of norovirus
winter vomiting disease
increase in severity with emergence of new strains
norovirus transmission
fecal oral
highly contagious
infected food handlers
long duration of shed (up to 2 weeks)
at risk individuals for norovirus
adults in close quarters
children
50% associated w long term care facilities
90% of cruise ship outbreaks
infectivity of norovirus
environmentally stable
withstands freezing and heating
alcohol based hand sanitizers ineffective
symptoms duration of norovirus
1-2 days
diagnosis of norovirus
clinical, molecular
rotavirus virology
dsRNA, nonenveloped
wheel like on EM
rotavirus seasonality
late winter/ early spring
rotavirus transmission
fecal oral
contaminated fomites
at risk individuals for rotavirus
children (4-24 mo)
most infected by 5 years
adults usually have partial immunity and decreased severity
infectivity of rotavirus
environmentally stable
symptom duration of rotavirus
3-8 days
rotavirus vaccine
live attenuated
85-98% protection against hospitalization
74-87% protection against illness
orally dosed to infants
diagnosis of rotavirus
antigen in stool
molecular
adenovirus virology
dsDNA, nonenveloped
>50 serotypes infect humans (serotypes 40/41 most associated with ge)
diverse array of symptoms
seasonality of adenovirus
none
transmission of adenovirus
fecal oral
at risk individuals for adenovirus
children (2nd to rotavirus)