B vitamins

Question 1

B1

Answer 1

Thiamin.
Modified to: Thiamin Pyrophosphate (TPP).
Active Site: Thiazolium Ring.
Carries Aldehydes.

Question 2

B2

Answer 2

Riboflavin.
Modified to FMN, FAD.
Active Site: Isoalloxanine Ring
Carries: 2H+, 2e-

Question 3

B3

Answer 3

Niacin.
Modified to: NAD+, NADP+
Active Site: Nicotinamide Ring
Carries: 1H+, 2e-

Question 4

B5

Answer 4

Pantothenate.
Modified to: CoA
Active Site: Thiol (from Cys)
Carries: Acyl groups

Question 5

B6

Answer 5

Pyridoxin.
Modified to: Pyradoxal Phosphate (PLP)
Active Site: Schiff base (Lys w/ a base substrate)
Carries: Amino acids

Question 6

B7

Answer 6

Biotin.
Modified to: “Prosthetic” Lys group
Active Site: Ureido Ring
Carries: CO2

Question 7

B9

Answer 7

Folate.
Modified to: Tetrahydrofolate (THF).. reduction
Active Site: Pteridine N5 and/or N10
Carries: One carbon units

Question 8

B12

Answer 8

Cobalamine
Modified to: AdoB12 or MetB12
Active Site: Corrin ring (Co- or CoCH2)
Carries: AdoB12, Hydrogen radical; MetB12, Methyl