B. Biology

Question 1

intro to immune 1

Answer 1

lymp nodes contain T, B cells, and plasma cells

Question 2

spleen

Answer 2

largest lymphoid issue, filter blood borne pathogens

Question 3

immune cells diagram

Answer 3

lymphoid progenitor: T, B, NK

myeloid: neut, baso, eosino, mast, macrophages

Question 4

humoral immunity

Answer 4

Antibody, by B cells

Question 5

cell mediated

Answer 5

T cells, and other immune cells

Question 6

APC: Macro, Bcells, dendritic cells

Answer 6

activate T cell-> release mediators produce inflammatory response

Question 7

Dendritic cells

Answer 7

activate t cell by clonal expansion

Question 8

Thelper

Answer 8

activated by CD4 receptors and TC receptors

Question 9

Tcyt

Answer 9

have TCR and CD8, kill virally infected cells

Question 10

Basophils release histamine

Answer 10

eosinophils release leukotienes, cytokines (interleukins, TNFa)

Question 11

Mast cells

Answer 11

Activated by IgE, degranulation and release of histamines

Question 12

IgE bound to mast cells though Fc e receptor

Answer 12

Atopy produce more IgE

Question 13

Cytokines

Answer 13

Interleukins: IL-1 pro inflammatory
IL-8 chemokine for neutrophils (attrracts)

Cysteinyl Leukotrienes: contract smooth muscle, attract leukocyte

TNFa: pro inflammatory, chemotactic(attract inflammatory cells)

Question 14

Allergy. Phase 1: induction

Answer 14

Allergen caught by APC - present to T cells - produce interleukins - stimulate B cells produce IgE - IgE bind to basophils and mast cells

Question 15

Degranulation

Answer 15

Vasodilation/oedema
Bronchoconstriction
Mucus production