B & B Exam 2 Flashcards
Intra- vs Inter- cellular
Within the cell vs between cells
Axon Hillock function
Origin of action potential, determines excitatory/inhibitory impulses
What are the three types of neurons?
Motor, sensory and interneurons
What do MOTOR neurons do?
Sends signals from the brain and spinal cord to muscles
What do SENSORY neurons do?
Bring information to the CNS
What do INTERNEURONS do?
(connects sensory and motor) Associate sensory and motor activity within the CNS
AKA association neurons
What are the five types of glia?
Ependymal cells
Astrocytes
Microglia
Oliodendroglia
Schwann Cells
What do Ependymal cells do?
Small, ovoid; found in the walls of the ventricles; Makes and secretes CSF
What do Astrocytes cells do?
- Star shaped
- Structural support for neurons
- Transport substances between neurons and capillaries (glucose) and BBB
- Scar tissue formation
- Enhancement of brain activity by providing fuel to active brain regions
What do Microglia cells do?
- Originates in the blood as offshoot of immune system
- Phagocytosis scavenging of debris/dead cells
- Brain is protected because the blood-brain barrier
- prevents immune system cells from entering
- Monitor the health of brain tissue
- Identify and attack foreign tissue
- When brain cells are damaged, they invade the area to provide growth factors that aid in repair
What do Oliodendroglia cells do?
In CNS, myelinates axon
What do Schwann Cells do?
In PNS, myelinates axons
What is the main purpose of the blood brain barrier?
- Protection system
- Adaptive wall along sides of blood vessels in the brain
Protects from toxic chemicals, viruses, harmful substances - Pumps nutrients from cerebral blood to and from the brain into blood
- Molecules that dissolve in fat (lipophilic) of the vessel membrane cross passively (lead)
What are endothelial cells and what structures are composed of these cells?
form the walls of capillaries in the brain circulatory system; central to the BBB
What substances can cross the blood-brain barrier passively?
CO2, O2, and small uncharged molecules