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autonomics Flashcards

1
Q

rapidly hydrolyzed by AChE

A

Acetylcholine (TOPNOTCH)

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2
Q

resistant to AChE

A

Betanechol (TOPNOTCH)

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3
Q

for Bladder and bowel atony

A

Betanechol (TOPNOTCH)

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4
Q

Nonselective muscarinic and nicotinic agonist , used topically for glaucoma treatment

A

Carbachol (TOPNOTCH)

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5
Q

Partial muscarinic agonist; used for treatment of Glaucoma, Sjogren’s syndrome and Sicca syndrome

A

Pilocarpine (TOPNOTCH)

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6
Q

Adverse Effects of Acetylcholine

A

CNS stimulation, miosis, cyclospasm, brochoconstriction, excessive GI and GU smooth muscle contraction, increased secretory activity of sweat gland, airways etc, vasodilation (TOPNOTCH)

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7
Q

activates autonomic post ganglionic neurons (both sympathetic and parasympathetic) and skeletal muscle neuromuscular end plants

A

Nicotine(TOPNOTCH)

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8
Q

used exclusively for smoking cessation

A

Varenicline (TOPNOTCH)

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9
Q

for Myasthenia gravis diagnosis (Tensilon test)

A

Edrophonium (TOPNOTCH)

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10
Q

for Myasthenia gravis treatment; reversal of nondepolarizing muscular blockade

A

Neostigmine (TOPNOTCH)

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11
Q

Long Acting Cholinesterase Inhibitors used as Scabicide and Insecticide

A

Malathion, Parathion (TOPNOTCH)

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12
Q

Competitively blocks all muscarinic receptors, antagonizes histamine and serotonin ; for motion sickness, dec. acid secretion in the GIT

A

Scopolamine (TOPNOTCH)

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13
Q

DOC for organophosphate poisoning

A

Atropine (TOPNOTCH)

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14
Q

for bradycardia, hypersalivation and to decrease airway secretion during general anesthesia

A

Atropine (TOPNOTCH)

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15
Q

Mydriatic, cycloplegic in eye examinations

A

Homatropine, Cyclopentolate, Tropicamide (TOPNOTCH)

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5
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16
Q

Competitive nonselective antagonist at muscarinic receptors ; for BA and COPD, not as effective as SABAs but less tachycardia and arrhythmia

A

Ipratropium, Tiotropium (TOPNOTCH)

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17
Q

Nonselective muscarinic antagonist which reduces detrussor smooth muscle tone spasms

A

Oxybutinin (TOPNOTCH)

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18
Q

for decreasing urgency in mild cystitis and dec. bladder spasm after urologic surgery

A

Oxybutinin (TOPNOTCH)

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19
Q

Usual antidote for early stage (48h) cholinesterase inhibitor poisoning, Must be administered before 6-8 hours of organophosphate bond with cholinesterase occurs

A

Pralidoxime (TOPNOTCH)

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20
Q

Competitively blocks all Nn nicotinic Ach receptors ; for Hypertensive emergencies (obsolete)

A

Hexamethonium, Mecamylamine, Trimethaptan (TOPNOTCH)

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21
Q

DOC for Anaphylaxis

A

Epinephrine (TOPNOTCH)

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22
Q

used for Cardiac arrest, anaphylaxis, asthma, COPD, Hemostasis

A

Epinephrine (TOPNOTCH)

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23
Q

for cardiogenic Shock and heart failure

A

Norepinephrine (TOPNOTCH)

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24
Q

causes vasodilation in splanchnic and renal blood vessels ; for cardiogenic Shock and heart failure

A

Dopamine (TOPNOTCH)

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25
Q

Beta nonselective sympathomimetic, for Asthma

A

Isoproterenol (TOPNOTCH)

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26
Q

SE: Rebound nasal congestion, hypertension, stroke, MI

A

Phenylephrine (TOPNOTCH)

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27
Q

A2 agonist, for Hypertension, Cancer pain, opioid withdrawal

A

Clonidine (TOPNOTCH)

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28
Q

Sedation, rebound hypertension, dry mouth

A

Clonidine (TOPNOTCH)

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29
Q

Sedation, positive Coomb’s test (Hemolytic anemia)

A

Methyldopa (TOPNOTCH)

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30
Q

A2 agonist; reserved for ophthalmologic use in glaucoma for reduction of intraocular pressure

A

Apraclonidine, Brimonidine (TOPNOTCH)

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31
Q

B1 agonist, for cardiogenic shock and acute heart failure

A

Dobutamine (TOPNOTCH)

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32
Q

DOC as Asthma reliever, Rapid development of tolerance

A

Albuterol/Salbutamol (TOPNOTCH)

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33
Q

D1 agonist, for Hypertension

A

Fenoldopam (TOPNOTCH)

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34
Q

D2 agonist, restores dopamine actions in the CNS for Parkinson’s disease, prolactinemia

A

Bromocriptine (TOPNOTCH)

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35
Q

Irreversibly blocks A1 and A2 receptors resulting to indirect baroreflex activation

A

Phenoxybenzamine (TOPNOTCH)

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36
Q

Reversible A1 and A2 receptor antagonist, for Pheochromocytoma and Rebound hypertension

A

Phentolamine (TOPNOTCH)

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37
Q

Blocks A1, for Benign Prostatic Hyperplasia, Hypertension

A

Prazosin, Doxazosin, Terazosin (TOPNOTCH)

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38
Q

Slightly selective A1a blockade causing relaxation of prostatic smooth muscles > vascular smooth muscle ; for BPH

A

Tamsulosin (TOPNOTCH)

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39
Q

Beta blockade > A1 blockade

A

Labetalol (TOPNOTCH)

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40
Q

Blocks B1 and B2 receptors

A

Propranolol, Nadolol, Timolol (TOPNOTCH)

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41
Q

B1 > B2 blockade

A

Metoprolol, Atenolol, Alprenolol, Betaxolol, Nebivolol (TOPNOTCH)

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42
Q

B1, B2 with intrinsic sympathomimetic (partial agonist) effect

A

Pindolol, Acebutolol, Carteolol, Bopindolol, Oxprenolol, Celiprolol, Penbutolol (TOPNOTCH)

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43
Q

Beta blockade > A1 blockade

A

Carvedilol, Medoxalol, Bucindolol, Labetalol (TOPNOTCH)

How well did you know this?
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2
3
4
5
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44
Q

B1 > B2 blockade; for rapid control of BP and arrhythmias, thyrotoxicosis and myocardial ischemia intraoperatively ; for Supraventricular tachycardia

A

Esmolol (TOPNOTCH)

How well did you know this?
1
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2
3
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5
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45
Q

BB with direct vasodilating effect

A

Nebivolol (TOPNOTCH)

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46
Q

BB with local anesthetic effect

A

Propranolol (TOPNOTCH)

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47
Q

BB which is safe in pregnant patients

A

Labetalol (TOPNOTCH)

How well did you know this?
1
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2
3
4
5
Perfectly
48
Q

Mydriasis without cycloplegia

A

Phenylephrine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Cholinesterase Inhbitors with poor lipid solubility, oral, DOA: 30min-2h

A

Neostigmine (TOPNOTCH)

How well did you know this?
1
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2
3
4
5
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50
Q

rapidly hydrolyzed by AChE

A

Acetylcholine (TOPNOTCH)

How well did you know this?
1
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2
3
4
5
Perfectly
51
Q

resistant to AChE

A

Betanechol (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

for Bladder and bowel atony

A

Betanechol (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Nonselective muscarinic and nicotinic agonist , used topically for glaucoma treatment

A

Carbachol (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Partial muscarinic agonist; used for treatment of Glaucoma, Sjogren’s syndrome and Sicca syndrome

A

Pilocarpine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Adverse Effects of Acetylcholine

A

CNS stimulation, miosis, cyclospasm, brochoconstriction, excessive GI and GU smooth muscle contraction, increased secretory activity of sweat gland, airways etc, vasodilation (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

activates autonomic post ganglionic neurons (both sympathetic and parasympathetic) and skeletal muscle neuromuscular end plants

A

Nicotine(TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

used exclusively for smoking cessation

A

Varenicline (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

for Myasthenia gravis diagnosis (Tensilon test)

A

Edrophonium (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

for Myasthenia gravis treatment; reversal of nondepolarizing muscular blockade

A

Neostigmine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

Long Acting Cholinesterase Inhibitors used as Scabicide and Insecticide

A

Malathion, Parathion (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

Competitively blocks all muscarinic receptors, antagonizes histamine and serotonin ; for motion sickness, dec. acid secretion in the GIT

A

Scopolamine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

DOC for organophosphate poisoning

A

Atropine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

for bradycardia, hypersalivation and to decrease airway secretion during general anesthesia

A

Atropine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

Mydriatic, cycloplegic in eye examinations

A

Homatropine, Cyclopentolate, Tropicamide (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

Competitive nonselective antagonist at muscarinic receptors ; for BA and COPD, not as effective as SABAs but less tachycardia and arrhythmia

A

Ipratropium, Tiotropium (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

Nonselective muscarinic antagonist which reduces detrussor smooth muscle tone spasms

A

Oxybutinin (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

for decreasing urgency in mild cystitis and dec. bladder spasm after urologic surgery

A

Oxybutinin (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

Usual antidote for early stage (48h) cholinesterase inhibitor poisoning, Must be administered before 6-8 hours of organophosphate bond with cholinesterase occurs

A

Pralidoxime (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

Competitively blocks all Nn nicotinic Ach receptors ; for Hypertensive emergencies (obsolete)

A

Hexamethonium, Mecamylamine, Trimethaptan (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

DOC for Anaphylaxis

A

Epinephrine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

used for Cardiac arrest, anaphylaxis, asthma, COPD, Hemostasis

A

Epinephrine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

for cardiogenic Shock and heart failure

A

Norepinephrine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

causes vasodilation in splanchnic and renal blood vessels ; for cardiogenic Shock and heart failure

A

Dopamine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

Beta nonselective sympathomimetic, for Asthma

A

Isoproterenol (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

SE: Rebound nasal congestion, hypertension, stroke, MI

A

Phenylephrine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

A2 agonist, for Hypertension, Cancer pain, opioid withdrawal

A

Clonidine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

Sedation, rebound hypertension, dry mouth

A

Clonidine (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

Sedation, positive Coomb’s test (Hemolytic anemia)

A

Methyldopa (TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

A2 agonist; reserved for ophthalmologic use in glaucoma for reduction of intraocular pressure

A

Apraclonidine, Brimonidine (TOPNOTCH)

80
Q

B1 agonist, for cardiogenic shock and acute heart failure

A

Dobutamine (TOPNOTCH)

81
Q

DOC as Asthma reliever, Rapid development of tolerance

A

Albuterol/Salbutamol (TOPNOTCH)

82
Q

D1 agonist, for Hypertension

A

Fenoldopam (TOPNOTCH)

83
Q

D2 agonist, restores dopamine actions in the CNS for Parkinson’s disease, prolactinemia

A

Bromocriptine (TOPNOTCH)

84
Q

Irreversibly blocks A1 and A2 receptors resulting to indirect baroreflex activation

A

Phenoxybenzamine (TOPNOTCH)

85
Q

Reversible A1 and A2 receptor antagonist, for Pheochromocytoma and Rebound hypertension

A

Phentolamine (TOPNOTCH)

86
Q

Blocks A1, for Benign Prostatic Hyperplasia, Hypertension

A

Prazosin, Doxazosin, Terazosin (TOPNOTCH)

87
Q

Slightly selective A1a blockade causing relaxation of prostatic smooth muscles > vascular smooth muscle ; for BPH

A

Tamsulosin (TOPNOTCH)

88
Q

Beta blockade > A1 blockade

A

Labetalol (TOPNOTCH)

89
Q

Blocks B1 and B2 receptors

A

Propranolol, Nadolol, Timolol (TOPNOTCH)

90
Q

B1 > B2 blockade

A

Metoprolol, Atenolol, Alprenolol, Betaxolol, Nebivolol (TOPNOTCH)

91
Q

B1, B2 with intrinsic sympathomimetic (partial agonist) effect

A

Pindolol, Acebutolol, Carteolol, Bopindolol, Oxprenolol, Celiprolol, Penbutolol (TOPNOTCH)

92
Q

Beta blockade > A1 blockade

A

Carvedilol, Medoxalol, Bucindolol, Labetalol (TOPNOTCH)

93
Q

B1 > B2 blockade; for rapid control of BP and arrhythmias, thyrotoxicosis and myocardial ischemia intraoperatively ; for Supraventricular tachycardia

A

Esmolol (TOPNOTCH)

94
Q

BB with direct vasodilating effect

A

Nebivolol (TOPNOTCH)

95
Q

BB with local anesthetic effect

A

Propranolol (TOPNOTCH)

96
Q

BB which is safe in pregnant patients

A

Labetalol (TOPNOTCH)

97
Q

Mydriasis without cycloplegia

A

Phenylephrine (TOPNOTCH)

98
Q

Cholinesterase Inhbitors with poor lipid solubility, oral, DOA: 30min-2h

A

Neostigmine (TOPNOTCH)

99
Q

rapidly hydrolyzed by AChE

A

Acetylcholine (TOPNOTCH)

100
Q

resistant to AChE

A

Betanechol (TOPNOTCH)

101
Q

for Bladder and bowel atony

A

Betanechol (TOPNOTCH)

102
Q

Nonselective muscarinic and nicotinic agonist , used topically for glaucoma treatment

A

Carbachol (TOPNOTCH)

103
Q

Partial muscarinic agonist; used for treatment of Glaucoma, Sjogren’s syndrome and Sicca syndrome

A

Pilocarpine (TOPNOTCH)

104
Q

Adverse Effects of Acetylcholine

A

CNS stimulation, miosis, cyclospasm, brochoconstriction, excessive GI and GU smooth muscle contraction, increased secretory activity of sweat gland, airways etc, vasodilation (TOPNOTCH)

105
Q

activates autonomic post ganglionic neurons (both sympathetic and parasympathetic) and skeletal muscle neuromuscular end plants

A

Nicotine(TOPNOTCH)

106
Q

used exclusively for smoking cessation

A

Varenicline (TOPNOTCH)

107
Q

for Myasthenia gravis diagnosis (Tensilon test)

A

Edrophonium (TOPNOTCH)

108
Q

for Myasthenia gravis treatment; reversal of nondepolarizing muscular blockade

A

Neostigmine (TOPNOTCH)

109
Q

Long Acting Cholinesterase Inhibitors used as Scabicide and Insecticide

A

Malathion, Parathion (TOPNOTCH)

110
Q

Competitively blocks all muscarinic receptors, antagonizes histamine and serotonin ; for motion sickness, dec. acid secretion in the GIT

A

Scopolamine (TOPNOTCH)

111
Q

DOC for organophosphate poisoning

A

Atropine (TOPNOTCH)

112
Q

for bradycardia, hypersalivation and to decrease airway secretion during general anesthesia

A

Atropine (TOPNOTCH)

113
Q

Mydriatic, cycloplegic in eye examinations

A

Homatropine, Cyclopentolate, Tropicamide (TOPNOTCH)

114
Q

Competitive nonselective antagonist at muscarinic receptors ; for BA and COPD, not as effective as SABAs but less tachycardia and arrhythmia

A

Ipratropium, Tiotropium (TOPNOTCH)

115
Q

Nonselective muscarinic antagonist which reduces detrussor smooth muscle tone spasms

A

Oxybutinin (TOPNOTCH)

116
Q

for decreasing urgency in mild cystitis and dec. bladder spasm after urologic surgery

A

Oxybutinin (TOPNOTCH)

117
Q

Usual antidote for early stage (48h) cholinesterase inhibitor poisoning, Must be administered before 6-8 hours of organophosphate bond with cholinesterase occurs

A

Pralidoxime (TOPNOTCH)

118
Q

Competitively blocks all Nn nicotinic Ach receptors ; for Hypertensive emergencies (obsolete)

A

Hexamethonium, Mecamylamine, Trimethaptan (TOPNOTCH)

119
Q

DOC for Anaphylaxis

A

Epinephrine (TOPNOTCH)

120
Q

used for Cardiac arrest, anaphylaxis, asthma, COPD, Hemostasis

A

Epinephrine (TOPNOTCH)

121
Q

for cardiogenic Shock and heart failure

A

Norepinephrine (TOPNOTCH)

122
Q

causes vasodilation in splanchnic and renal blood vessels ; for cardiogenic Shock and heart failure

A

Dopamine (TOPNOTCH)

123
Q

Beta nonselective sympathomimetic, for Asthma

A

Isoproterenol (TOPNOTCH)

124
Q

SE: Rebound nasal congestion, hypertension, stroke, MI

A

Phenylephrine (TOPNOTCH)

125
Q

A2 agonist, for Hypertension, Cancer pain, opioid withdrawal

A

Clonidine (TOPNOTCH)

126
Q

Sedation, rebound hypertension, dry mouth

A

Clonidine (TOPNOTCH)

127
Q

Sedation, positive Coomb’s test (Hemolytic anemia)

A

Methyldopa (TOPNOTCH)

128
Q

A2 agonist; reserved for ophthalmologic use in glaucoma for reduction of intraocular pressure

A

Apraclonidine, Brimonidine (TOPNOTCH)

129
Q

B1 agonist, for cardiogenic shock and acute heart failure

A

Dobutamine (TOPNOTCH)

130
Q

DOC as Asthma reliever, Rapid development of tolerance

A

Albuterol/Salbutamol (TOPNOTCH)

131
Q

D1 agonist, for Hypertension

A

Fenoldopam (TOPNOTCH)

132
Q

D2 agonist, restores dopamine actions in the CNS for Parkinson’s disease, prolactinemia

A

Bromocriptine (TOPNOTCH)

133
Q

Irreversibly blocks A1 and A2 receptors resulting to indirect baroreflex activation

A

Phenoxybenzamine (TOPNOTCH)

134
Q

Reversible A1 and A2 receptor antagonist, for Pheochromocytoma and Rebound hypertension

A

Phentolamine (TOPNOTCH)

135
Q

Blocks A1, for Benign Prostatic Hyperplasia, Hypertension

A

Prazosin, Doxazosin, Terazosin (TOPNOTCH)

136
Q

Slightly selective A1a blockade causing relaxation of prostatic smooth muscles > vascular smooth muscle ; for BPH

A

Tamsulosin (TOPNOTCH)

137
Q

Beta blockade > A1 blockade

A

Labetalol (TOPNOTCH)

138
Q

Blocks B1 and B2 receptors

A

Propranolol, Nadolol, Timolol (TOPNOTCH)

139
Q

B1 > B2 blockade

A

Metoprolol, Atenolol, Alprenolol, Betaxolol, Nebivolol (TOPNOTCH)

140
Q

B1, B2 with intrinsic sympathomimetic (partial agonist) effect

A

Pindolol, Acebutolol, Carteolol, Bopindolol, Oxprenolol, Celiprolol, Penbutolol (TOPNOTCH)

141
Q

Beta blockade > A1 blockade

A

Carvedilol, Medoxalol, Bucindolol, Labetalol (TOPNOTCH)

142
Q

B1 > B2 blockade; for rapid control of BP and arrhythmias, thyrotoxicosis and myocardial ischemia intraoperatively ; for Supraventricular tachycardia

A

Esmolol (TOPNOTCH)

143
Q

BB with direct vasodilating effect

A

Nebivolol (TOPNOTCH)

144
Q

BB with local anesthetic effect

A

Propranolol (TOPNOTCH)

145
Q

BB which is safe in pregnant patients

A

Labetalol (TOPNOTCH)

146
Q

Mydriasis without cycloplegia

A

Phenylephrine (TOPNOTCH)

147
Q

Cholinesterase Inhbitors with poor lipid solubility, oral, DOA: 30min-2h

A

Neostigmine (TOPNOTCH)

148
Q

rapidly hydrolyzed by AChE

A

Acetylcholine (TOPNOTCH)

149
Q

resistant to AChE

A

Betanechol (TOPNOTCH)

150
Q

for Bladder and bowel atony

A

Betanechol (TOPNOTCH)

151
Q

Nonselective muscarinic and nicotinic agonist , used topically for glaucoma treatment

A

Carbachol (TOPNOTCH)

152
Q

Partial muscarinic agonist; used for treatment of Glaucoma, Sjogren’s syndrome and Sicca syndrome

A

Pilocarpine (TOPNOTCH)

153
Q

Adverse Effects of Acetylcholine

A

CNS stimulation, miosis, cyclospasm, brochoconstriction, excessive GI and GU smooth muscle contraction, increased secretory activity of sweat gland, airways etc, vasodilation (TOPNOTCH)

154
Q

activates autonomic post ganglionic neurons (both sympathetic and parasympathetic) and skeletal muscle neuromuscular end plants

A

Nicotine(TOPNOTCH)

155
Q

used exclusively for smoking cessation

A

Varenicline (TOPNOTCH)

156
Q

for Myasthenia gravis diagnosis (Tensilon test)

A

Edrophonium (TOPNOTCH)

157
Q

for Myasthenia gravis treatment; reversal of nondepolarizing muscular blockade

A

Neostigmine (TOPNOTCH)

158
Q

Long Acting Cholinesterase Inhibitors used as Scabicide and Insecticide

A

Malathion, Parathion (TOPNOTCH)

159
Q

Competitively blocks all muscarinic receptors, antagonizes histamine and serotonin ; for motion sickness, dec. acid secretion in the GIT

A

Scopolamine (TOPNOTCH)

160
Q

DOC for organophosphate poisoning

A

Atropine (TOPNOTCH)

161
Q

for bradycardia, hypersalivation and to decrease airway secretion during general anesthesia

A

Atropine (TOPNOTCH)

162
Q

Mydriatic, cycloplegic in eye examinations

A

Homatropine, Cyclopentolate, Tropicamide (TOPNOTCH)

163
Q

Competitive nonselective antagonist at muscarinic receptors ; for BA and COPD, not as effective as SABAs but less tachycardia and arrhythmia

A

Ipratropium, Tiotropium (TOPNOTCH)

164
Q

Nonselective muscarinic antagonist which reduces detrussor smooth muscle tone spasms

A

Oxybutinin (TOPNOTCH)

165
Q

for decreasing urgency in mild cystitis and dec. bladder spasm after urologic surgery

A

Oxybutinin (TOPNOTCH)

166
Q

Usual antidote for early stage (48h) cholinesterase inhibitor poisoning, Must be administered before 6-8 hours of organophosphate bond with cholinesterase occurs

A

Pralidoxime (TOPNOTCH)

167
Q

Competitively blocks all Nn nicotinic Ach receptors ; for Hypertensive emergencies (obsolete)

A

Hexamethonium, Mecamylamine, Trimethaptan (TOPNOTCH)

168
Q

DOC for Anaphylaxis

A

Epinephrine (TOPNOTCH)

169
Q

used for Cardiac arrest, anaphylaxis, asthma, COPD, Hemostasis

A

Epinephrine (TOPNOTCH)

170
Q

for cardiogenic Shock and heart failure

A

Norepinephrine (TOPNOTCH)

171
Q

causes vasodilation in splanchnic and renal blood vessels ; for cardiogenic Shock and heart failure

A

Dopamine (TOPNOTCH)

172
Q

Beta nonselective sympathomimetic, for Asthma

A

Isoproterenol (TOPNOTCH)

173
Q

SE: Rebound nasal congestion, hypertension, stroke, MI

A

Phenylephrine (TOPNOTCH)

174
Q

A2 agonist, for Hypertension, Cancer pain, opioid withdrawal

A

Clonidine (TOPNOTCH)

175
Q

Sedation, rebound hypertension, dry mouth

A

Clonidine (TOPNOTCH)

176
Q

Sedation, positive Coomb’s test (Hemolytic anemia)

A

Methyldopa (TOPNOTCH)

177
Q

A2 agonist; reserved for ophthalmologic use in glaucoma for reduction of intraocular pressure

A

Apraclonidine, Brimonidine (TOPNOTCH)

178
Q

B1 agonist, for cardiogenic shock and acute heart failure

A

Dobutamine (TOPNOTCH)

179
Q

DOC as Asthma reliever, Rapid development of tolerance

A

Albuterol/Salbutamol (TOPNOTCH)

180
Q

D1 agonist, for Hypertension

A

Fenoldopam (TOPNOTCH)

181
Q

D2 agonist, restores dopamine actions in the CNS for Parkinson’s disease, prolactinemia

A

Bromocriptine (TOPNOTCH)

182
Q

Irreversibly blocks A1 and A2 receptors resulting to indirect baroreflex activation

A

Phenoxybenzamine (TOPNOTCH)

183
Q

Reversible A1 and A2 receptor antagonist, for Pheochromocytoma and Rebound hypertension

A

Phentolamine (TOPNOTCH)

184
Q

Blocks A1, for Benign Prostatic Hyperplasia, Hypertension

A

Prazosin, Doxazosin, Terazosin (TOPNOTCH)

185
Q

Slightly selective A1a blockade causing relaxation of prostatic smooth muscles > vascular smooth muscle ; for BPH

A

Tamsulosin (TOPNOTCH)

186
Q

Beta blockade > A1 blockade

A

Labetalol (TOPNOTCH)

187
Q

Blocks B1 and B2 receptors

A

Propranolol, Nadolol, Timolol (TOPNOTCH)

188
Q

B1 > B2 blockade

A

Metoprolol, Atenolol, Alprenolol, Betaxolol, Nebivolol (TOPNOTCH)

189
Q

B1, B2 with intrinsic sympathomimetic (partial agonist) effect

A

Pindolol, Acebutolol, Carteolol, Bopindolol, Oxprenolol, Celiprolol, Penbutolol (TOPNOTCH)

190
Q

Beta blockade > A1 blockade

A

Carvedilol, Medoxalol, Bucindolol, Labetalol (TOPNOTCH)

191
Q

B1 > B2 blockade; for rapid control of BP and arrhythmias, thyrotoxicosis and myocardial ischemia intraoperatively ; for Supraventricular tachycardia

A

Esmolol (TOPNOTCH)

192
Q

BB with direct vasodilating effect

A

Nebivolol (TOPNOTCH)

193
Q

BB with local anesthetic effect

A

Propranolol (TOPNOTCH)

194
Q

BB which is safe in pregnant patients

A

Labetalol (TOPNOTCH)

195
Q

Mydriasis without cycloplegia

A

Phenylephrine (TOPNOTCH)

196
Q

Cholinesterase Inhbitors with poor lipid solubility, oral, DOA: 30min-2h

A

Neostigmine (TOPNOTCH)

pharma (8 decks)

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