Autonomic Simplified Flashcards
Where would you find Alpha one receptors?
Liver, saliva glands, and smooth muscle
What neurotransmitters work on alpha-1 receptors?
Epinephrine norepinephrine and dopamine
You should think sympathetic response when discussing which alpha type receptor?
Alpha one
There are no alpha one agonist drugs to study, but what are two examples of alpha one antagonist?
Prazosin (Minipress)
Tamsulosin (Flomax)
Which type of alpha receptors are found on presynaptic neurons, the pancreas, platelets, and in the CNS? Which neurotransmitters affect these receptors?
Alpha 2
Epinephrine and norepinephrine
Which alpha receptors provide a negative feedback to decrease catecholamine release?
Alpha 2
What is one example of an alpha two agonist medication?
Clonidine
In what three areas would you find beta one receptors?
Heart, kidneys, and adipose tissue
What neurotransmitters work on beta one receptors?
Epinephrine, norepinephrine and dopamine
There are no agonist drugs to remember for beta ones, but what are two examples of beta one antagonists?
Propranolol and Atenolol
Where would you find beta two receptors? Give three locations.
Liver, smooth muscle and blood vessels
What neurotransmitter works on beta 2 receptors?
Epinephrine
What is one example of a beta two agonist?
Albuterol
What is one example of a beta two antagonist?
Propranolol
Vasoconstriction is stimulated by (alpha 1, beta) receptors while vasodilation is stimulated by (alpha 1, beta) receptors.
Alpha 1
Beta
What are three indications to take alpha 1 agonists?
Hypotension
Nasal congestion
Pupil dilation (eye exam)
Three indications for alpha 2 agonists?
HTN
ADHD
ODD
Three indications for beta 1 agonists?
Cardiac arrest
Heart failure
Shock
Two indications for beta 2 agonists?
Asthma
Premature labor contractions
What are three indications for alpha 1 antagonists? These work by causing vasodilation.
Nasal congestion
Hypotension
Pupil dilation for eye exam
What are four indications for nonselective beta antagonists?
Angina
Tachyarrhythmias
Migraine prophylaxis
Anxiety
What are three indications for selective beta 1 antagonists?
HTN
Angina
Post myocardial infarction as antidysrhythmic
What medications end in “-lol”?
Beta blockers
Alpha-beta blockers
Which meds end in “-sin”?
Alpha 1 antagonists
What meds contain “-chol” in the name?
Muscarinic agonists (Bethanechol; except pilocarpine)
What are three cholinesterase inhibitors?
Neostigmine
Pyridostigmine
Donepezil
What meds end in “-ine”? Examples: atropine, scopolamine
Cholinergic blockers
What are the main uses of cholinergic drugs?
Decrease intraocular pressure in glaucoma
Atony of GI tract and urinary bladder
Diagnose and treat MG
Which med is used to treat anticholinergic toxicity?
Physostigmine
Two examples of Cholinergic agonists?
Bethanechol (Urecholine)
Pilocarpine
What drug is given for cholinergic toxicity?
Atropine
