Autonomic Physiology Flashcards

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1
Q

What does autonomic nervous system mean? what muscle type does it act on.

A

Means it controls the things you don’t think about

Smooth and cardiac

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2
Q

What does the somatic nervous system do? What muscle type does it act on

A

Controls the voluntary stuff, is sensory. Controls skeletal muscle

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3
Q

Autonomic vs Somatic;

Describe how specialized each it, the type of receptor used and if if they excite/inhibit the target

A

Somatic - is s a specialized NMJ, has ionotropic receptors and always excites target

Autonomic - Less specialized, used metabotropic receptors and may excite or inhibit

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4
Q

Talking now only about autonomic - what does the sympathetic system do?

A

Fight or flight - has coordinated effects

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5
Q

What does the parasympathetic system do?

A

Rest and digest - has independent effects

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6
Q

What spinal cord region does the sympathetic nervous system flow from?

A

Thoracic and Lumbar

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7
Q

In sympathetic - is the pre-ganglionic fibres longer or shorter than the post-ganglionic fibres?

A

Shorter - ganglia lies close to spinal cord

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8
Q

In the sympathetic - what acts on what receptor at the ganglia

A

Preganglonic fibres release acetylcholine (Ach) which act on nicotinic receptors

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9
Q

In sympathetic - what do post-ganglionic fibres release and what receptor does it act on?

A

Noradrenaline - acts on alpha or beta receptors

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10
Q

In parasympathetic - what spinal cord region do the fibres exit from?

A

Cranial and Sacral

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11
Q

In parasympathetic - are the pre-ganglionic fibres longer or shorter than post?

A

Longer - ganglia lies closer to target

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12
Q

In parasympathetic - what acts on what receptor at the ganglia?

A

Ach acts on nicotinic receptors

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13
Q

In parasympathetic - what do post-ganglionic fibres release and on what receptor?

A

Ach again on muscarinic receptors

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14
Q

Do postganglonic fibres always follow the rules?

A

No - some sympathetic fibres innervate sweat glands and some release non-adrenergic non-cholinergic transmitters

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15
Q

Of the two (paraS or S) which has the hormonal component?

A

Sympathetic

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16
Q

How does all these fibres and stuff cause all these different effects?

A

Depends on what is released and what receptor it acts on

17
Q

The eye - Sympathetic system - How does it make the eye dilate?

A

Activates Beta 2 receptor causing ciliary muscle to relax and eye focuses far away

Activates alpha 1 receptor, radial muscle on iris contracts and makes pupils larger

18
Q

The eye - parasympathetic system - How does it make the eye constrict?

A

Activates muscarinic receptors causing ciliary muscle to contracts & eye focuses close up

Activates muscarinic receptors causing sphincter muscle to contract & makes pupil smaller

19
Q

The heart - Sympathetic system - How does it make the heart beat faster?

A

Activates beta 1 receptors on pacemaker cells and myocytes causing increase in heart rate and strength of contraction

20
Q

The heart - parasympathetic system - How does it make the heart beat slower?

A

Activates muscarinic receptors on pacemaker cells decreasing heart rate

Has little effect on myocytes therefore little effect on strength of contraction

21
Q

The lungs - Sympathetic system - How does it make the lungs dilate?

A

Activates beta 2 receptors on smooth muscle of airways causing them to relax and dilate

22
Q

The lungs - parasympathetic system - How does it make the airways constrict

A

Activates muscarinic receptors making smooth muscle constrict

23
Q

Blood vessels - Sympathetic system - How does it make blood flow decrease?

A

Acts on alpha 1 receptors causing smooth muscle to contract and blood flow in that region decreases

24
Q

Blood vessels - Sympathetic system - How does it make blood flow INCREASE

A

Acts on beta 2 receptors causing smooth muscle to relax and blood flow in that region increases

25
Q

Why in blood flow - is it just the sympathetic system used?

A

Cause during fight or flight, bp needs to increase BUT blood is sent to where its needed and is taken from where its not…

26
Q

The gut - sympathetic - how does it decrease gut motility?

A

Activates alpha/beta receptors on the smooth muscle of the gut decreasing motility

Acts on alpha receptors in pancreas inhibiting secretion of enzymes

27
Q

The gut - parasympathetic - how does it increase gut motility?

A

Activates muscarinic receptors on smooth muscle of gut which increases motility

Acts on muscarinic receptors in pancreas increasing secretion of enzymes

28
Q

Salivary glands - Symp - how does it dry mouth?

A

Activates beta receptors stimulating thick secretion rich in enzymes

29
Q

Salivary glands - ParaSymp - how does it make mouth drool

A

Acts on muscarinic receptors which stimulates a profuse of water solution

30
Q

Basically - tissues have dual innervation and effects can be complementary or antagonistic

A

True - I give up with these examples