Autonomic Nervous System Drugs Flashcards
ANS (Autonomic Nervous System)
is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels.
SNS (Sympathetic Nervous System)
controls “fight-or-flight” responses
PNS (Parasympathetic Nervous System
slows our heart and breathing rates, lowers blood pressure and promotes digestion.
Neuron
the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the electrical signals at every step in between.
Afferent
the nerve fibers responsible for bringing sensory information from the outside world into the brain.
Efferent
the nerve fibers responsible for carrying signals from the brain to the peripheral nervous system in order to initiate an action.
Autonomic Drugs
used clinically to either imitate or inhibit the normal functions of the sympathetic and parasympathetic nervous systems.
Agonist
a drug that binds to the receptor, producing a similar response to the intended chemical and receptor.
Antagonist
a drug that binds to the receptor either on the primary site, or on another site, which all together stops the receptor from producing a response.
Selective Drugs
refers to a drug’s ability to preferentially produce a particular effect and is related to the structural specificity of drug binding to receptors.
Non-selective Drugs
drugs that affects many different tissues or organs.
Adrenergic
any of various drugs that mimic or interfere with the functioning of the sympathetic nervous system by affecting the release or action of norepinephrine and epinephrine.
Cholinergic
a category of pharmaceutical agents that act upon the neurotransmitter acetylcholine, the primary neurotransmitter within the parasympathetic nervous system (PNS).
Catecholamines
hormones that the brain, nerve tissues, and adrenal glands produce. The body releases catecholamines in response to emotional or physical stress. Catecholamines are responsible for the body’s “fight-or-flight” response. Dopamine, adrenaline, and noradrenaline are all catecholamines.
Non-Catecholamines
the second group of adrenergic drugs. Non-catecholamines do not have hydroxyl groups on the benzene ring. Most non-catecholamines are effective orally. They have moderate to a poor affinity for adrenoceptors.