Autonomic Nervous System drugs

Question 1

Pupil Dilation

Answer 1

Sympathetic

Question 2

Increases heart rate

Answer 2

Sympathetic

Question 3

Increases Peristalsis

Answer 3

Parasympathetic

Question 4

Decreases Heart Rate

Answer 4

Parasympathetic

Question 5

Constricts blood vessels

Answer 5

Sympathetic

Question 6

Dilates blood vessels

Answer 6

Parasympathetic

Question 7

Relaxes uterine muscles

Answer 7

Sympathetic

Question 8

Increases salivation

Answer 8

Parasympathetic

Question 9

Activates receptor by binding to that receptor

Answer 9

Agonist

Question 10

Binds to receptor and prevents agonist from stimulating it

Answer 10

Antagonist

Question 11

Agonist properties

Answer 11

affinity, intrinsic activity, effect

Question 12

What is Receptor Theory?

Answer 12

The idea that drugs act by binding to receptors, the application of receptor models to explain drug behaviour.

Question 13

Effects of beta-1 agonists?

Answer 13

Increase rate and force of contraction of the heart

Question 14

Bind to receptors found presynaptically to decrease the amount of norepinephrine release.
Basically, these drugs decrease sympathetic outflow.
Therefore, you will see a decrease in vasoconstriction. This results in a drop in blood pressure/hypotension and can also cause bradycardia

Answer 14

Receptors: Alpha 2

Question 15

Increases the heart rate and force of contraction, increases renin secretion which increases blood pressure.
Beta _ receptors are located in the kidney but primarily in the heart. When stimulated, these receptors increase myocardial contractility and heart rate.

Negative effect: dysthymias, angina

Answer 15

Beta 1

Question 16

Effects of beta-2 agonists?

Answer 16

Bronchodilation, vasodilation, relaxation of visceral smooth muscle (GIT, bladder, and uterus), glycogenolysis, muscle tremor

Question 17

Carries info from the outside/structures to be processed; from the PNS (Peripheral Nervous System) to the CNS (Central Nervous System)

Answer 17

Afferent/Sensory

Question 18

Carries info from the inside to the outside/structures to command or control them, from the CNS (Central Nervous System) to the PNS (Peripheral Nervous System)

Answer 18

Efferent/Motor

Question 19

Direct-Acting drugs fall into two general categories _____ and ______.

Answer 19

Selective & Non-selective

Question 20

What division of the PNS is voluntary and controls skeletal muscles?

Answer 20

The somatic nervous system is voluntary and controls skeletal muscle.

Question 21

What division is involuntary and controls smooth muscle, cardiac muscle, and glands?

Answer 21

The autonomic/visceral nervous system is involuntary and controls involuntary muscles (cardiac and smooth muscle) and glands.