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Pharmacology 2100 > Autonomic Nervous System Agonists and Antagonists > Flashcards

Autonomic Nervous System Agonists and Antagonists Flashcards

1
Q

What is phenylephrine?

A

Alpha 1 Agonist

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2
Q

Therapeutic effect of phenylephrine?

A

Decrease in nasal congestion
Maintain BP

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3
Q

Max number of days to use phenylephrine?

A

3 days

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4
Q

Where are Beta 2 receptors located?

A

Lungs
Arterioles
Uterus
Liver
GI Tract

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5
Q

Where are Beta 1 receptors located?

A

Heart
Coronary Vessels
Kidneys

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6
Q

What are the Adrenergic Receptors?

A

Alpha 1
Alpha 2
Beta 1
Beta 2

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7
Q

3 Ways to inactive neurotransmitter?

A

Diffusion
Re-uptake
Enzyme degradation or transformation

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8
Q

What is the parasympathetic system neurotransmitter?

A

acetylcholine

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9
Q

Where are muscarinic receptors located?

A

Internal organs

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10
Q

Where are nicotinic receptors located?

A

Skeletal Muscles
Motor Nerves

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11
Q

What are the cholinergic receptors?

A

Muscarinic
Nicotinic

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12
Q

What is a cholinergic crisis?

A

Excessive parasympathetic stimulation
-miosis
-N/V
-urinary incontinence
-increase in secretions
-tachycardia then bradycardia
-hyperglycemia

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13
Q

What medication do you give in cholinergic crisis?

A

Atropine

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14
Q

What to adrenergic antagonists do?

A

Block SNS
Decrease Heart Rate, BP and Anxiety

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15
Q

What is a cholinergic agonist medication?

A

bethanechol

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16
Q

What are the therapeutic effects of epinephrine?

A

Decrease allergic reactions
Treat anaphylaxis

17
Q

Is epinephrine selective or nonselective?

A

nonselective

18
Q

What are the therapeutic effects of propranolol?

A

Decrease hypertension, angina, and anxiety

19
Q

Side effects of propranolol?

A

IMPOTENCE
hypoglycemia in diabetics

20
Q

What is propranolol?

A

beta adrenergic antagonist
(nonselective for beta 1 or beta 2)

21
Q

What is prazosin?

A

Alpha 1 antagonist

22
Q

What are the therapeutic effects of prazosin?

A

Lower HTN, treat BPH, and PTSD

23
Q

What are the therapeutic effects of bethanecol?

A

decrease urine retention
increase peristalsis and GI secretions

24
Q

What is albuterol?

A

Beta 2 agonist

25
Q

Therapeutic effects of albuterol?

A

improve asthma, COPD

26
Q

What are 3 Adrenergic Agonists?

A

Albuterol
Epinephrine
Phenylephrine

27
Q

Where are Alpha 1 Receptors located?

A

Blood vessels
Eyes
Bladder
Prostate

28
Q

Where are Alpha 2 Receptors located?

A

Blood Vessels
Smooth Muscle (GI)

29
Q

What is the neurotransmitter for the sympathetic nervous system?

A

Norepinephrine

30
Q

What medication is a muscarinic antagonist?

A

atropine sulfate

31
Q

What are the therapeutic effects of atropine sulfate?

A

Increase HR
Dilate pupils
Dry secretions
Slow GI tract
Treat cholinergic crisis

32
Q

Sxs of anticholinergic?

A

Can’t Pee
Can’t See
Can’t Spit
Can’t Shit

33
Q

Beta 1 Agonist sxs?

A

Increased Heart Rate
Increased BP
Increased Renin secretion

34
Q

Beta 2 Agonists sxs?

A

Bronchiole dilation
Decreased GI motility
Increased blood flow to skeletal muscles
Increase blood glucose

35
Q

Alpha 2 Agonists sxs?

A

Decrease in vasoconstriction
Decrease in BP
Decrease in GI motility

36
Q

Alpha 1 Agonists sxs?

A

Increase force of heart contraction
vasoconstriction
Increase BP
Pupil Dilation
Prostate contraction and ejaculation

Pharmacology 2100 (7 decks)

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