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Pathophys Neurology Test > autonomic nervous system > Flashcards

autonomic nervous system Flashcards

1
Q

autonomic pregangilionic neurons are

A

myelinated

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2
Q

post ganglionic neurons in autonomic system are

A

unmyelinated

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3
Q

SNS innervagion is from

A

T1-L2: thoracolumbar cell bodies

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4
Q

parasympathetic innervation is

A

craniosacral: cranial nerve nuclei and sacral region of the spinal cord

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5
Q

no PNS trunk instead—

A

its ganglia all exist in the periphery, close to the organs they innervate

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6
Q

PNS does not go to

A

uterus, cardiac muscle, uterus, sweat glands and goosebumps skeletal muscle and only a few BV

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7
Q

sympathetic preganglionic fibers

A

NT: acetylcholine
receptor: cholinergic

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8
Q

sympathetic postganglionic

A

NT: norepinephrine
Receptor: adrenergic

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9
Q

parasympatethic pre and post ganglionic

A

NT: acetylcholine
receptor: adrenergic

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10
Q

___ is a modified sympathetic ganglion

A

adrenal medulla

hit by ACH pumps out E, NE into blood

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11
Q

a-adrenergic receptors

A

a1: excitiation : squeeze things, BV, urethral sphincter
a2: relaxation/ inhibition

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12
Q

b-adrenergic receptors

A

B1: increase HR and contracitility, renin release
B2: facilitates all the rest: relaxes muscles of bronchi and bladder
B3: mediates lipolysis and thermogeneisi

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13
Q

nicotinic receptors

A

PNS
all ACH receptors on postganglionic cells are nicotinic
all at NMJ

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14
Q

muscarinic locations

A

cardiac, exocrine glands, CNS, GI and smooth muscle

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15
Q

MSG is a ___ dz

A

nicotinic receptor dz

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16
Q

how treat MSG?

A

neostigmine: ACHE inhibitor
steroids
plasmaphoresis

17
Q

most common location for primary spinal cord injury

A

C1-L2

18
Q

primary spinal injury

A

crush, torsion, severing

19
Q

Secondary spinal cord injury

A

swelling, delayed tissue destruction

20
Q

spinal cord swelling in __ region = life threatening

A

cervical spinal region

21
Q

spinal shock

A

complete loss of reflex function, flaccid paralysis, sensory deficit and loss of bladder and rectal control in all segments below the level of the lesion

22
Q

complications of spinal shock

A

poor venous circulation

23
Q

excitotoxicity

A

when damage to CNS release glutamate and aspartate which leads to cellular damage - depends on many factors

24
Q

neurogenic shock

A

due to loss of sympathetic outflow - presynaptic neurons cannot get to SNS truknk

occurs with cervical or upper thoracic spinal cord injury

25
Q

autonomic dysfunction

A

occurs with lesions above T7

sudden massive reflex SNS discharge with no opposing PSNS

26
Q

sx seen with autonomic dysfucntion

A

HTN up to 300 mg
brady cardia
pounding HA, blurred vision, sweating above the lesion with flushing of the skin, piloerection

Pathophys Neurology Test (5 decks)

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