Autonomic Nervous System Flashcards

1
Q

What does the ANS innervate?

A

Cardiac muscle, smooth muscle, and secretory cells

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2
Q

Is there direct control involved in ANS?

A

No, they are under autonomic function

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3
Q

Fight or Flight

A

Sympathetic

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4
Q

Rest and Digest

A

Parasympathetic

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5
Q

What does the Somatic nervous system innervate?

A

Skeletal muscle

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6
Q

Where is the PSNS origin in the spinal cord?

A

Craniosacral

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7
Q

Where is the SNS origin in the spinal cord?

A

Thoracolumbar

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8
Q

What are some ANS neurotransmitters?

A
Acetylcholine
Norepinepherine
Epinepherine
Dopamine
Histamine
Seratonin
NO
Etc...
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9
Q

Is acetylcholine released from a presynaptic or postsynaptic neuron?

A

Presynaptic

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10
Q

What are the two types of cholinergic receptors?

A

Nicotinic and Muscarinic

**Remember acetylcholine binds to these

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11
Q

What type of receptor are Nicotinic receptors? (ionotropic or metabotropic)

A

Ionotropic

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12
Q

What type of receptor are Muscarinic receptors? (ionotropic or metabotropic)

A

Metabotropic

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13
Q

What binds to adrenergic receptors?

A

Epinepherine, norepinepherine, dopamine

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14
Q

What are the two types of adrenergic receptors?

A

Alpha (1 and 2) and Beta (1 and 2)

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15
Q

Mimetics

A

Drugs that stimulate (mimic) Autonomic effects

So,

For parasympathomimetic you will have parasympathetic signs and for sympathetomimetic you will have sympathetic signs

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16
Q

Lytics

A

Drugs that block autonomic effects

So,

For parasympatholytic you will see sympathetic signs and for sympatholytic you will see parasympathetic signs

17
Q

Sympathetic effects of the eye

A

Relaxation of the ciliary muscle and contraction of the iris radial muscle (mydriasis)

18
Q

Parasympathetic effects of the eye

A

Contraction of ciliary muscles and iris sphincter muscle

19
Q

Sympathetic effects of the heart (B-1)

A

Increased heart rate (tachycardia)
Increased contractility
Increased automacity and conduction of AV node

20
Q

Parasympathetic effects of the heart

A

Decreased heart rate (bradycardia)
Decreased contractility
Decreased AV node conduction

21
Q

Sympathetic effects of the vasculature

A

a-1 vasoconstriction
b-2 vasodilation
a-2 various

22
Q

Parasympathetic effects of the vasculature

A

Vasodilation through release of NO

23
Q

Sympathetic effects of the lung

A

b-2 bronchodilation, increase respiratory secretions

a-2 decrease secretions

24
Q

Parasympathetic effects of the lung

A

Bronchoconstriction

increase respiratory secretions

25
Q

Sympathetic effects of the GI tract

A

a-1, b-1, b-2
decrease motility
close sphincters
inhibit secretion

26
Q

Parasympathetic effects of the GI tract

A

increase motility
relax sphincters
stimulate secretions

27
Q

Sympathetic effects of the bladder

A

B-2 relax detrusor muscle

a-1 contract sphincter

28
Q

Parasympathetic effects of the bladder

A

contract destrusor

relax sphincter

29
Q

Autonomic drugs can be:

A

direct acting or indirect acting

30
Q

What does it mean if an ANS drug is direct acting?

A

The drug acts directly on the receptor (agonists and antagonists)

31
Q

What does it mean if an ANS drug is indirect acting?

A

The drug interacts with something other than the receptor