autonomic nerous system 2

Question 1

dale principle

Answer 1

1 neurone 1 NT

Question 2

different terminals what is actually happening

Answer 2

1 neurone can also release >1 NT at the same terminal

Question 3

dennervation supersensitivity

Answer 3

responds more easily than normal
if supply declines sensitivity increases
compensation just like in alzhemirs

Question 4

mechanism for dennervation supersensitivity

Answer 4

receptor proliferation or loss of NT removal or increase post synaptic membrane excitability threshold

Question 5

neuromodulation

Answer 5

process whereby the NT acts presynaptically to modulate release of NT presynaptically
eg Noradren acting on post ganglionic parasympathetic synapse to prevent ach release

Question 6

ach also does what to Noradren

Answer 6

inhibit it being released in the heart

Question 7

homotrophic inhibition

Answer 7

NT release acts back on its pre synaptic terminal to inhibit further release
creating a feedback loop

Question 8

neruomodulators act to influences transmission without

Answer 8

acting as a transmitter itself

effects are slower than transmission

Question 9

co transmitters also

Answer 9

control the release of NT to activate or inhibit pre (quick)

Question 10

non adrenergic non cholinergic transmission

Answer 10

Other nts released from presynapse and acts on post-synaptic R
Effects to enhance or inhibit Ad or cholinergic transmission