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Neuro Block 3-RG > Autonomic Innervation of the Eye > Flashcards

Autonomic Innervation of the Eye Flashcards

1
Q

Ciliary muscle control

A

parasympathetic

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2
Q

Mydriasis

A

contracts pupillary dilator muscle

alpha-1 receptor NE

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3
Q

Alpha-1 receptor agonist use

A

pupillary dialation

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4
Q

Superior tarsal muscle receptor

A

alpha-1 receptor NE

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5
Q

Parasympathetic receptor type

A

mAChR

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6
Q

What muscle contracts in parasympathetic innervation of the eye?

A

ciliary muscle contraction

pupil constricts

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7
Q

Sympathomimetics

A

mimic sympathetic effects

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8
Q

Parasympathetic antagonist: the classic

A

atropine

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9
Q

Atropine

A

parasympathetic antagonist

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10
Q

What is the mechanism of cocaine with regards to the eye?

A

blocks neuronal reuptake of NE

keeps pupil dialated

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11
Q

What is the mechanism of amphetamines with regards to the eye?

A

promotes fusion of NE vesicles

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12
Q

Pathophys of Horner’s syndrome?

A

CNS/PNS damage to sympathetic nerve

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13
Q

What is phenylephrine?

A

alpha-1 agonist

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14
Q

Phenylephrine use

A

eye dilation

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15
Q

You give cocaine and the pupil dilates, what does that mean?

A

sympathetic innervation is intact

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16
Q

You give amphetamines and the pupil dilates, what does that mean?

A

postganglionic nerve is intact

17
Q

You give cocaine and the pupil does not dilate but amphetamines do dilate pupil, what does that mean?

A

uh-oh

you probably cut the postganglionic sympathetic nerve

18
Q

Where are nAChR located in sympathetic response?

A

cell bodies of postganglionic sympathetic and parasympathetics*

19
Q

Pilocarpine

A

muscarinic antagonist

20
Q

If eye does not respond to pilocarpine, where is the problem?

A

in the eye

21
Q

If eye does respond to pilocarpine with miosis, where must the problem be?

A

third nerve palsy

22
Q

What sympathetic receptor does the ciliary muscle use and what is the sympathetic response?

A

beta-2 receptor for NE

response is ciliary muscle relaxation

23
Q

What sympathetic receptor does the superior tarsal muscle use and what is the sympathetic response?

A

alpha-1 receptor for NE

contraction of muscle, eyelid opening

24
Q

Action of phenylephrine

A

direct stimulation of alpha-1 androgenic receptors

25
Q

What is latanoprost and what is it used for?

A

prostaglandin derivative

Tx of glaucoma

26
Q

Acetazolamide mechanism of action in glaucoma

A

CA inhibitor

protons cannot be used to exchange for Na+ from blood that can be used to pump into aqueous humor

Neuro Block 3-RG (23 decks)

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