Autoimmune systemic Flashcards
Photosensitivity, arthritis, hemolytic anemia & recurrent oral ulcers
Lupus
Polymositis
Muscle weakness Increase CK Increase aldolase \+ ANA \+ Anti-Jo1
Polymyalgia Rheumatica
Joint Pain No muscle pain No muscle weakness Normal CK Normal Aldolase
Anti-Smith and anti-dsDNA antibodies
Systemic Lupus Erythematosus
Anti-histone antibodies
Drug-induced lupus
Anti-centromere antibodies
CREST scleroderm
Anti-centromere antibodies
Diffuse Systemic scleroderma
Anti-topoisomerase antibodies
Polymyositis
Anti-Jo-1 antibodies
Sjogren syndrome
Anti-Ro antibodies
Sjogren syndrome
Arthritis, dry mouth, and dry eyes
Sjogrens
SS-A (anti-Ro) and/or SS-B (anti-La)
Sjogren syndrome
triad of autoimmunity, noninflammatory vasculopathy, and excess collagen deposition with fibrosis
sclerosis of skin, puffy taut skin without wrinkles
ASSOCIATED WITH WHAT ANTIBODIES
Diffuse scleroderma
anti- Scl-70 and anti-DNA topoisomerase I antibody
What is CREST syndrome?
Calcinosis Raynaud phenomenon Esophageal dysmotility Sclerodactyly Telangiectasia