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John Step 1 > Autoimmune Markers > Flashcards

Autoimmune Markers Flashcards

1
Q

What disease is associated with SS-A (Ro)

A

Sjogren’s Syndrome

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2
Q

What disease is associated with SS-B (La)

A

Sjogren’s Syndrome (more specific than SS-A)

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3
Q

What disease is associated with Monosodium urate crystals

A

gout

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4
Q

What disease is associated with Calcium pyrophosphate crystals

A

pseudogout

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5
Q

What disease is associated with Antinuclear Abs

A

SLE (not specific though)

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6
Q

What disease is associated with Anti dsDNA Abs

A

SLE (very specific with poor prognosis)

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7
Q

What disease is associated with Anti-Smith Abs

A

SLE very specific but not prognostic

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8
Q

What disease is associated with Antihistone Abs

A

Drug induced SLE

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9
Q

What disease is associated with Non caseating granulomas

A

Sarcoidosis

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10
Q

What disease is associated with positive ANA & Anti-Jo-1

A

Polymyositis (aka dermatomyositis)

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11
Q

What disease is associated with Anti-Scl-70 Ab

A

Scleroderma

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12
Q

What disease is associated with AntiCentromere Ab

A

CREST Syndrome

Calcinosis, Raynauds, Esophageal dysmotility, Sclerodactyly, Telangiectasia

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13
Q

Anti-Ach Receptor

A

Myasthenia Gravis

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14
Q

Antibasement Membrane

A

Goodpastures

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15
Q

Antithyroglobulin

A

Hashimoto Thyroiditis

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16
Q

Antimitochondrial

A

Primary Biliary Cirrhosis

17
Q

Anti-TSH receptor

A

Graves Disease

18
Q

Anti U1 RNP

A

mixed connective tissue disease

19
Q

c-ANCA

A

Wegeners

20
Q

p-ANCA

A

microscopic polyangiitis, churg-strauss

John Step 1 (7 decks)

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