Autoimmune Hepatitis Flashcards
1
Q
Presentation of Autoimmune hepatitis?
A
Severity dependent: asymptomatic-cirrhosis range
Fever, Jaundice + hepatosplenomegaly
2
Q
Investigating Autoimmune Hepatitis
A
1) Bloods - abnormal LFTs
(others depend on extent of liver damage)
2) Antibody: ANA/ASMA + ALKM-1/ALC-1
3) Liver Biopsy
3
Q
Management of Autoimmune Hepatitis?
A
Immunosuppression
1) Prednisolone
2) Azathiaporine
Liver transplant if unsuccessful
4
Q
Types 1 vs Type II?
A
Type I - ANA/ASMA +ve (10%), ALKM-1/ALC -ve
Type II - young children, ANA/ASMA -ve
