Autoimmune Diseases Flashcards

0
Q

Target of HLA DR3 on insulin dep DM

A

Beta islet cells, anti-islet cell

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1
Q

Insulin dependent DM

HLA (2)

A

HLA-DR3

HLA-DR4

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2
Q

Target of HLA-DR4 on insulin dep DM

A

Insulin

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3
Q

Intrinsic factor

Anti intrinsic factor

A

Pernicious anemia

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4
Q

Cell surface antigen on anti parietal cells

Parietal cells

A

Pernicious anemia

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5
Q

Grave’s disease HLA (2)

A

HLA-DR3

HLA-BW35

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6
Q

Target of HLA-DR3 on grave’s dse

A

TSH receptor

Anti-thyroglobulin

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7
Q

Target of HLA-BW35 on grave’s dse

A

On thyroid gland

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8
Q

Hashimoto’s thyroiditis target (2)

A

Thyroglobulin

Thyroid peroxidase

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9
Q

Goodpasture’s syndrome target (2)

A

Basement membrane

Antiglomerular basement membrane

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10
Q

Primary biliary cirrhosis target

A

Antimitochondrial

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11
Q

Multiple sclerosis target

A

Antimyelin

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12
Q

ITP target

Immune thrombocytopenic purpura

A

Antiplatelet

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13
Q

HLA of RA

A

HLA-DR4

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14
Q

HLA of SLE (2)

A

HLA-DR2

HLA-DR3

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15
Q

Antigen of SLE

A

Ds-DNA
ANA
ENA
Phospholipid

16
Q

Associated antibodies of SLE

A

Anti DNA
ANTINUCLEAR
antiribosome
Anti DNP

17
Q

Myasthenia gravis HLA

A

Conplex

Age dependent

18
Q

Myasthenia gravis antigen

A

Acetyl choline receptor

19
Q

Myasthenia gravis associated autoantibodies

A

Antiacetylcholine receptor binding

Antiacetylcholine receptor blocking

20
Q

Scleroderma HLA

A

HLA-DR3

21
Q

Assoc antibodies scleroderma

A

Anticentriole

Anti-Scl

22
Q

Sjogren’s syndrome HLA

A

HLA-DR3

23
Q

Assoc autoantibodies sjogren’s syndrome

A

Anti-SS-A

Anti-SS-B

24
Q

Polymyositis assoc autoantibodies

A

Anti-Jo-I
Anti-Ku
Anti-Mi-I
Anti-PM-I