Autoantibody Associations Flashcards

0
Q

Anti-phospholipid syndrome

A

Anti-cardiolipin

Lupus anticoagulant

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1
Q

Addison’s disease

A

Anti-21-hydroxylase

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2
Q

Autoimmune haemolytic anaemia

A

Red blood cell autoantibodies (warm or cold)

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3
Q

Autoimmune hepatitis

A

Anti-nuclear
Anti-smooth muscle
Anti-liver/kidney macrosomal-I
Perinuclear ANCA (pANCA)

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4
Q

Churg-Strauss syndrome

A

pANCA (MPO-ANCA)

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5
Q

Coeliac disease

A

Anti-endomysial
Anti-tissue transglutaminase
Anti-reticulin
Anti-gliadin

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6
Q

Diffuse cutaneous scleroderma

A

Anti-Scl-70
Polymerase 1, 2 and 3
Rheumatoid factor
Anti-nuclear

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7
Q

Goodpasture syndrome

A

Anti-glomerular basement membrane

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8
Q

Graves’ disease

A

Anti-TSH receptor

Anti-peroxidase

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9
Q

Hashimoto’s thyroiditis

A

TSH-receptor-blocking antibodies

Anti-peroxidase

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10
Q

Lambert-Eaton myasthenic syndrome

A

Anti-P/Q-type voltage gated calcium channels

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11
Q

Limited cutaneous scleroderma

A

Anti-centromere
Rheumatoid factor
Anti-nuclear

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12
Q

Mixed connective tissue disease

A

Anti-U1-RNP

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13
Q

Myasthenia gravis

A

Anti-acetylcholine receptor

Anti-nuclear

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14
Q

Paraneoplastic conditions

A
Anti-YO
Anti-Hu
Anti-Ri
Anti-MA
Anti-CV2/CRMP5
Anti-amphiphysin
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15
Q

Pernicious anaemia

A

Anti-parietal cell

Anti-intrinsic factor

16
Q

Polyarteritis nodosa

A

pANCA

17
Q

Polymyositis

A

Anti-Jo-1
Anti-nuclear
Rheumatoid factor

18
Q

Dermatomyositis

A

Anti-Jo-1
Anti-nuclear
Rheumatoid factor

19
Q

Primary biliary cirrhosis

A

Anti-mitochondrial

Specifically anti-pyruvate dehydrogenase complex E2/E3 binding protein

20
Q

Rheumatoid disease

A

Rheumatoid factor
Anti-nuclear
Anti-CCP

21
Q

Sjögren syndrome

A

Anti-Ro (SS-A)
Anti-La (SS-B)
Rheumatoid factor
Anti-nuclear

22
Q

Systemic Lupus Erythematosus

A
dsDNA
Rheumatoid factor
Anti-nuclear
Anti-Ro (SS-A)
Anti-Sm
Anti-U1-RNP
Anti-cardiolipin
23
Q

Wegener syndrome

A
Cytoplasmic ANCA (cANCA)
(PR3-ANCA)