Autoantibodies + Rheum Flashcards
Addisons Autoantibodies
Anti-21-hydroxylase
Anti-phospholipid syndrome Autoantibodies
Anti-cardiolipin
Lupus anticoagulant
Autoimmune haemolytic anaemia Autoantibodies
RBC Autoantibodies (Classified as warm or cold depending on what temperature Autoantibodies attach to RBC)
Autoimmune hepatitis Autoantibodies
Anti-nuclear
Anti-smooth muscle
Anti-Liver/Kidney microsomal
pANCA
Churg strauss Autoantibodies
pANCA (MPO)
Coeliac Autoantibodies
Anti-endomysial
Anti-tissue transglutaminase
Anti-gliadin
Scleroderma Autoantibodies
Rheumatoid factor
ANA
Anti-centromere
Goodpasture’s Autoantibodies
Anti-glomerular basement membrane
Grave’s Autoantibodies
Anti-TSH receptor
Hashimoto’s thyroiditis Autoantibodies
TSH-receptor blocking antibodies
Myasthenia graves Autoantibodies
Anti-acetylcholine receptos antibodies
Pernicious anaemia Autoantibodies
Anti-parietal cell
Anti-intrinsic factor
Polyarteritis nodosa Autoantibodies
pANCA (MPO)
Poly/Dermatomyositis Autoantibodies
ANA
Rheumatoid factor
Anti-Jo
Rheumatoid disease Autoantibodies
Anti-CCP
Rheumatoid factor
Sjögren syndrome Autoantibodies
Rheumatoid factor
ANA
Anti-Ro
Anti-La
SLE Autoantibodies
Anti-Doublestranded DNA
Rheumatoid factor
ANA
Anti-Ro
Wegner syndrome (Granulomatosis with Polyangitis)
cANCA (PR3)
Synovial fluid analysis of gout
(Remember ‘N’)
Negatively birefringent Needles of sodium urate
Cloudy appearance
Synovial fluid analysis of pseudogout
(Remember P)
Positively birefringent rhomboids of sodium Pyrophosphate
cloudy appearance
What is sicca and what assoc with
What test is diagnostic
Dry eyes seen in Primary Sjögrens or in assoc with other rheumatological conditions
Schirmer test: filter paper to lower eyelid and left for 5 mins (normally 10mm will become wet. Less = dry eyes)
