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Hailey - IHO > Autoantibodies and Associated Disorder > Flashcards

Autoantibodies and Associated Disorder Flashcards

1
Q

Anti-ACh receptor

A

Myasthenia gravis

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2
Q

Anti-basement membrane

A

Goodpasture syndrome

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3
Q

Anticardiolipin

A

SLE, antiphospholipid syndrome

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4
Q

Lupus anticoagulant

A

SLE, antiphospholipid syndrome

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5
Q

Anticentromere

A

Limited scleroderma (CREST syndrome)

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6
Q

Anti-desmosome (anti-desmoglein)

A

Pemphigus vulgaris

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7
Q

Anti-dsDNA, anti-Smith

A

SLE

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8
Q

Anti-glutamic acid decarboxylase (GAD-65)

A

Type 1 diabetes mellitus

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9
Q

Antihemidesmosome

A

Bullous pemphigoid

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10
Q

Anti-histone

A

Drug-induced lupus

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11
Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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12
Q

Antimicrosomal, antithyroglobulin

A

Hashimoto thyroiditis

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13
Q

Antimitochondrial

A

1* biliary cirrhosis

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14
Q

Antinuclear antibodies

A

SLE, nonspecific

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15
Q

Antiparietal cell

A

Pernicious anemia

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16
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

17
Q

Anti-smooth muscle

A

Autoimmune hepatitis

18
Q

Anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjogren syndrome

19
Q

Anti-TSH receptor

A

Graves disease

20
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

21
Q

IgA anti-endomysial, IgA anti-tissue tranglutaminase

A

Celiac disease

22
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangiitis, eosinophiic granulomatosis with polyangiitis (Churg-Strauss sydrome)

23
Q

PR3-ANCA/c-ANCA

A

Granulomatosis with polyangiitis (Wegener)

24
Q

Rheumatoid factor (IgM antibody that targets IgG Fc region)

A

Rheumatoid arthritis

25
Q

Anti-CCP (more specific)

A

Rheumatoid arthritis

Hailey - IHO (5 decks)

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