Autoantibodies

Question 1

Anti-Ach receptor

Answer 1

Myasthania Gravis

Question 2

Anti-basement membrane

Answer 2

Goodpasture syndrome

Question 3

Anti-cardiolipin, Anti-beta2 glycoprotein

Answer 3

SLE, Antiphospholipid syndrome

Question 4

Anti-centromere

Answer 4

Limited scleroderma (CREST syndrome)

Question 5

Anti-desmosome (anti-desmoglein)

Answer 5

Pemphigus vulgaris

Question 6

Anti-dsDNA, Anti-Smith

Answer 6

SLE

Question 7

Anti-glutamic acid decarboxylase (GAD65)

Answer 7

Type 1 DM

Question 8

Anti-hemidesmosome

Answer 8

Bullous pemphigoid

Question 9

Anti-histone

Answer 9

Drug induced lupus

Question 10

Anti-Jo-1, Anti-SRP, Anti-Mi2

Answer 10

Polymyositis, dermatomyositis

Question 11

Antimicrosomal antithyroglobulin

Answer 11

Hashimoto thyroiditis

Question 12

Antimitochondrial

Answer 12

primary biliary cirrhosis

Question 13

Antinuclear Ab

Answer 13

SLE, nonspecific

Question 14

Anti-parietal cell

Answer 14

Pernicious anemia

Question 15

Anti-Scl 70 (Anti-DNA topoisomerase 1)

Answer 15

Scleroderma (diffuse)

Question 16

Anti smooth muscle

Answer 16

Autoimmune hepatitis

Question 17

Anti-SSA, Anti-SSB, (Ro, La)

Answer 17

Sjogren syndrome

Question 18

Anti TSH receptor

Answer 18

Graves disease

Question 19

Anti-U1 RNP (ribonucleotideprotein)

Answer 19

Mixed connective tissue disease

Question 20

IgA anti endomysial, IgA anti-tissue transglutaminase

Answer 20

Celiacs disease

Question 21

MPO-ANCA/ pANCA

Answer 21

Microscopic polyangitis eosinophilic granulomatosis with polyangitis (Churg Strauss)

Question 22

PR3-ANCA/c-ANCA

Answer 22

Granulomatosis with polyangitis (wegener)

Question 23

Rheumatoid factor (IgM attacks IgG Fc region), Anti-CCP

Answer 23

Rheumatoid arthritis

Question 24

Anti-cardiac muscle

Answer 24

Dressler’s syndrome