Autoantibodies

Question 1

Anti-ACh

Answer 1

Myasthenia Gravis

Question 2

Anti-basement membrane

Answer 2

Goodpasture Syndrome

Question 3

Anti-cardiolipin, lupus anticoagulant

Answer 3

SLE, Antiphospholipid syndrome (Blood clots)

Question 4

Anticentromere

Answer 4

CREST (Limited Scleroderma)

Question 5

Anti-desmoglein

Answer 5

Pemphigus Vulgaris

Question 6

anti-dsDNA, anti SMITH

Answer 6

SLE (Specific)

Question 7

Anti-glutamate decarboxylase

Answer 7

Type I DM

Question 8

Anti-hemidesmosome

Answer 8

Bullous Pemphigoid

Question 9

Antihistone

Answer 9

Drug Induced SLE (HIPP) Hydralazine, INH, Procainamide, Phenytoin

Question 10

Anti-Jo-1, anti-SRP, anti-Mi-2

Answer 10

Polymyositis, Dermatomyositis

Question 11

Antimicrosomal, antithyroglobulin

Answer 11

Hashimoto

Question 12

antimitochondrial

Answer 12

Primary Billiary Cirrhosis

Question 13

antinuclear antibodies (ANA)

Answer 13

nonspecific lupus (Screening)

Question 14

anti-scl70 (topoisomerase)

Answer 14

Diffuse Scleroderma

Question 15

Anit-smooth muscle

Answer 15

Autoimmune Hepatitis

Question 16

Anti-SSA, anti- SSB (Ro, La)

Answer 16

Sjogrens

Question 17

Anti-TSHr

Answer 17

Grav’es

Question 18

Anti-U1 RNP

Answer 18

MCTD

Question 19

c-ANCA

Answer 19

Wegener (Granulomatosis with polyangitis)

Question 20

IgA antiendomysial, IgA anti-tissue transglutaminase

Answer 20

Celiacs

Question 21

p-ANCA

Answer 21

Pauci immune GN

Microscopic Polyangitis, Churg-Strauss

Question 22

RF (Anti-antibody) (gM to IgG Fc) anti ccp more sepcific

Answer 22

Rheumatoid Arthritis