Auto abs and disease correlations Flashcards

1
Q

anti-Ach receptor

A

myasthenia gravis

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2
Q

anti-basement membrane

A

goodpasture syndrome

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3
Q

anti-cardiolipin, lupus nticoagulate

A

SLE

antiphospholipid syndrome

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4
Q

anti-centromere

A

limited scleroderma = CREST syndrome

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5
Q

anti-desomsonedesmogleuin

A

pepmphigus vulgaris

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6
Q

anti-dsDNA, anti-smithg

A

SLE

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7
Q

anit-glutamic acid decarboxylase/GAD-65

A

DM I

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8
Q

anti- hemidesmosome

A

bullous pemphigoid

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9
Q

anti-histone

A

drug-induced lupus

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10
Q

anti-jo-1, anti-SRP, anti-Mi-2

A

polymyositis, dermatomyositis

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11
Q

anti-microsomal, anti-thyroglobulin

A

hasihimoto thyroiditis

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12
Q

anti-mitochondrial

A

primary biliary cirrhosis

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13
Q

anti-nuclear antibodies

A

SLenonspecific

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14
Q

anti-parietal cell

A

pernicious anaemia

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15
Q

anti-scl-70/anti-DNA topoisomerase I

A

scleroderma - diffuse

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16
Q

anti-smooth muscle

A

autoimmune hepatitis

17
Q

anti-SSA, anti-SSB aka anti-Ro and anti-La

A

sjogren syndrome

18
Q

anti-TSH receptor

A

graves disease

19
Q

anti-U1 RNP (ribonucleoprotein)

A

mixed connective tissue disease

20
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

celiac disease

21
Q

MPO-ANCA/p-ANCA

A

Churg Strauss aka eosinophilis granulomatosis with poolyangiitis
microscopic polyangiitis

22
Q

PR3-ANCA/c-ANCA

A

granulomatosis with polyangiitis aka WEgener

23
Q
rheumatoid factor (IgM that targets Fc portion of Ig)
anti-CCP (more specific RULE IN)
A

rheumatoid arthritis