Auto abs and disease correlations

Question 1

anti-Ach receptor

Answer 1

myasthenia gravis

Question 2

anti-basement membrane

Answer 2

goodpasture syndrome

Question 3

anti-cardiolipin, lupus nticoagulate

Answer 3

SLE

antiphospholipid syndrome

Question 4

anti-centromere

Answer 4

limited scleroderma = CREST syndrome

Question 5

anti-desomsonedesmogleuin

Answer 5

pepmphigus vulgaris

Question 6

anti-dsDNA, anti-smithg

Answer 6

SLE

Question 7

anit-glutamic acid decarboxylase/GAD-65

Answer 7

DM I

Question 8

anti- hemidesmosome

Answer 8

bullous pemphigoid

Question 9

anti-histone

Answer 9

drug-induced lupus

Question 10

anti-jo-1, anti-SRP, anti-Mi-2

Answer 10

polymyositis, dermatomyositis

Question 11

anti-microsomal, anti-thyroglobulin

Answer 11

hasihimoto thyroiditis

Question 12

anti-mitochondrial

Answer 12

primary biliary cirrhosis

Question 13

anti-nuclear antibodies

Answer 13

SLenonspecific

Question 14

anti-parietal cell

Answer 14

pernicious anaemia

Question 15

anti-scl-70/anti-DNA topoisomerase I

Answer 15

scleroderma - diffuse

Question 16

anti-smooth muscle

Answer 16

autoimmune hepatitis

Question 17

anti-SSA, anti-SSB aka anti-Ro and anti-La

Answer 17

sjogren syndrome

Question 18

anti-TSH receptor

Answer 18

graves disease

Question 19

anti-U1 RNP (ribonucleoprotein)

Answer 19

mixed connective tissue disease

Question 20

IgA anti-endomysial, IgA anti-tissue transglutaminase

Answer 20

celiac disease

Question 21

MPO-ANCA/p-ANCA

Answer 21

Churg Strauss aka eosinophilis granulomatosis with poolyangiitis
microscopic polyangiitis

Question 22

PR3-ANCA/c-ANCA

Answer 22

granulomatosis with polyangiitis aka WEgener

Question 23

rheumatoid factor (IgM that targets Fc portion of Ig)
anti-CCP (more specific RULE IN)

Answer 23

rheumatoid arthritis