Atypical Parkinsonism

Question 1

Progressive Supranuclear Palsy

Answer 1

5 in 100k. Onset 63. Death in 7 years. No cases ever before 40 years old. Almost always sporadic.

Symmetrical Parkinsonism
Cognitive changes
Characteristic Supranuclear (upper motor neuron) palsy of vertical gaze
Early falls
Dysarthria
Dysphasia