Attention Deficit Hyperactivity Disorder (ADHD)

Question 1

What drugs are used for the management of ADHD?

Answer 1

Methylphenidate, atomoxetine, dexamphetamine, lisdexamphetamine.

Question 2

What class of drugs do methylphenidate and atomoxetine fall into?

Answer 2

CNS stimulants.

Question 3

Which drugs are used to treat ADHD in children who have not responded to treatment with methylphenidate or atomoxetine?

Answer 3

Dexamphetamine or lisdexamphetamine.

Question 4

What monitoring is required when patients are treated with atomoxetine?

Answer 4

Pulse, blood pressure, psychiatric symptoms, appetite, weight, and height should be recorded at initiation, following dose change, and at least every 6 months.

Question 5

What are the symptoms of the hepatic disorders associated with atomoxetine use? What should be done if this occurs?

Answer 5

Abdominal pain, unexplained nausea, malaise, darkening of the urine or jaundice. Medical attention must be sought.

Question 6

What psychiatric symptoms is rarely associated with atomoxetine use?

Answer 6

Risk of suicidal thoughts and behaviours. Report to GP any clinical worsening, suicidal thoughts or behaviour, irritability, agitation, or depression.

Question 7

Dexamphetamine and lisdexamphetamine should be discontinued when what symptoms occur in patients with Tourette’s syndrome?

Answer 7

If there is an exacerbation of tics.

Question 8

Why should height and weight be monitored in children treated with dexamphetamine and lisdexamphetamine?

Answer 8

Growth restriction can occur with long term use.