Antimigraine Drugs

Question 1

Which common painkillers are often an effective treatment for acute migraines?

Answer 1

Aspirin, paracetamol, or an NSAID.

Question 2

When treating acute migraine with simple analgesia, what further treatment may be required at the same time? Why?

Answer 2

Antiemetics as peristalsis can occur during a migraine, limiting the absorption of drugs and causing nausea.

Question 3

If simple analgesia is not adequate to treat a migraine, what can be tried?

Answer 3

5HT1-receptor agonists (triptans).

Question 4

When treating migraines with ergotamine, what symptoms are cause for immediate treatment cessation?

Answer 4

Peripheral vasospasm - stop treatment immediately if numbness or tingling of the extremities develops. Contact a doctor.

Question 5

42-year-old male with a history of migraine for 2 years previously responding to sumatriptan. Presents with an attack lasting over 16 hours which has not responded to sumatriptan after second dose. Which drug for prophylaxis would be most appropriate?

Answer 5

Propranolol.