Attachment and physical health Flashcards

1
Q

What is the Human Systems of Homeostasis?

A

Act to balance internal and external factors that may affect a system and keep it functioning within certain parameters

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2
Q

What are some regulatory systems that affect mental health?

A

Function:
Emotional Regulation

Systemic arousal/ energy conservation

Memory

Perception

Sleep /Wake cycle

Anatomical/Physiological Systems:
Limbic system

Autonomic system

Hippocampus/ Median Temporal lobe and Brain stem

Temporal Lobes and visual cortex

Pituitary /Endocrine

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3
Q

wHAT IS THE limbic system concerned with?

A

Concerned with the modulation of Emotions and Instincts

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4
Q

What does emotional dysregulation look like?

A

Extreme emotional outbursts
Uncontrolled temper
Self Harm
Difficulty maintaining relationships

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5
Q

Which parts of the nervous are involved in hyperarousal and hypoarousal?

A

Hyperarousal – Sympathetic Nervous system
Hypoarousal - Parasympathetic Nervous system

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6
Q

What are the causes of dysregulation?

A

Disrupted Attachment

Psychological Trauma (post Traumatic stress Disorder)

Temporary Effect of Trauma, Life Event or Stress

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7
Q

How was the attachment theory developed?

A

Bowlby First described concept: Human and animals attached to caregiver who feeds them

Lorenz ‘52– goslings follow parent not for food

Harlow ’58 – monkeys bond to cuddly pole with food rather than wire food pole

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8
Q

What is the theory behind attachment theory?

A

Attachment functions to protect infant from external dangers eg predators

Probable also emotional connection itself gives meaning/ has importance for our functioning

Social Animals

Essential for development of child

Affects individual through lifecycle

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9
Q

What is the neurophysiology behind attachment theory?

A

Oxytocin

Area of brain mainly involved limbic system and Right Hemisphere

Autonomic System Regulation - Separation – increase pulse and decreased temperature. If prolonged or frequent can lead to changes in cortisol and so affects bodies response to stress eg increase in infection

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10
Q

What is the window of tolerance

A

Window between 2 different bodily crises of hyper arousal - between flight/flight and freeze/dissociation

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11
Q

What are the types of attachment styles

A

Secure
Anxious
Ambivalent
Avoidant

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12
Q

What can affect attachment?

A

Iry caregiver emotionally unavailable eg depression

Drugs/ alcohol

Abuse/neglect
Anxious

Ambivalent

Avoidant

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13
Q

What is the secure attachment style?

A

Able to internally self regulate the emotional neural systems and response to environment From about 5 years upwards

Develop reciprocal social bonds

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14
Q

What is the anxious attachment style?

A

Maintaining attachment with a caregiver who is unpredictable
Clingy

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15
Q

What is the ambivalent attachment style

A

Alternate clinging with excessive submissiveness to no trust

Role reversal – parent cared for by child

Dysregulation of fear and anger

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16
Q

What is the avoidant attachment style

A

Child tries to minimise need for attachment to avoid rebuff

Remains in distant contact with the caregiver

When severe can ‘freeze’ when reunited with parent

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17
Q

How can we treat certain attachment styles?

A

NB Brain remains ‘plastic’ into early 20’s

Treatment (Dialectic Behaviour Therapy) can change pattern

Treat co- morbidities eg depression, self harm, eating disorders

18
Q

Elana is in frequent trouble at school for aggressive outbursts. She is often in fights with her peers.
Elana’s mother had severe obsessive compulsive disorder Elana was often left crying and hungry.
Support was sought from Elana’s paternal grandparents and treatment accessed by her Mum
Elana presents with a three year history of drug misuse, self harm and suicide attempts.
She also presents with low mood and pseudohallucinations
In addition she presents with food restriction, vomiting and weight loss
Elana has been admitted twice with ongoing low mood after taking overdoses and with severe weight loss and refusal to eat.

Elana has now been discharged from hospital but her eating remains restricted . She has no suicidal ideas and her mood has improved.

She is taking Fluoxetine and engaged in Dialectic Behaviour therapy
What do you think the diagnosis may be? (there may be more than one)

A

Eating Disorder
Depression
Drug Misuse
Attachment Disorder/Emerging personality disorder/borderline personality disorder

19
Q

Elana is in frequent trouble at school for aggressive outbursts. She is often in fights with her peers.
Elana’s mother had severe obsessive compulsive disorder Elana was often left crying and hungry.
Support was sought from Elana’s paternal grandparents and treatment accessed by her Mum
Elana presents with a three year history of drug misuse, self harm and suicide attempts.
She also presents with low mood and pseudohallucinations
In addition she presents with food restriction, vomiting and weight loss
Elana has been admitted twice with ongoing low mood after taking overdoses and with severe weight loss and refusal to eat.

Elana has now been discharged from hospital but her eating remains restricted . She has no suicidal ideas and her mood has improved.

She is taking Fluoxetine and engaged in Dialectic Behaviour therapy
What subspecialty would you refer to in AMH?

A

) Eating Disorder Service, Access Team, Drug Misuse service, Personality Disorder service…
Co-Ordinator is essential

20
Q

Elana is in frequent trouble at school for aggressive outbursts. She is often in fights with her peers.
Elana’s mother had severe obsessive compulsive disorder Elana was often left crying and hungry.
Support was sought from Elana’s paternal grandparents and treatment accessed by her Mum
Elana presents with a three year history of drug misuse, self harm and suicide attempts.
She also presents with low mood and pseudohallucinations
In addition she presents with food restriction, vomiting and weight loss
Elana has been admitted twice with ongoing low mood after taking overdoses and with severe weight loss and refusal to eat.

Elana has now been discharged from hospital but her eating remains restricted . She has no suicidal ideas and her mood has improved.

She is taking Fluoxetine and engaged in Dialectic Behaviour therapy
What are your main areas of concern/risk for Elana?

A

Risk of relapse of eating disorder, drug misuse or mood disorder and self harm.
Care in labelling of Personality disorder when young

21
Q

Elana is in frequent trouble at school for aggressive outbursts. She is often in fights with her peers.
Elana’s mother had severe obsessive compulsive disorder Elana was often left crying and hungry.
Support was sought from Elana’s paternal grandparents and treatment accessed by her Mum
Elana presents with a three year history of drug misuse, self harm and suicide attempts.
She also presents with low mood and pseudohallucinations
In addition she presents with food restriction, vomiting and weight loss
Elana has been admitted twice with ongoing low mood after taking overdoses and with severe weight loss and refusal to eat.

Elana has now been discharged from hospital but her eating remains restricted . She has no suicidal ideas and her mood has improved.

She is taking Fluoxetine and engaged in Dialectic Behaviour therapy
How would you go about transitioning her?

A

Early referral important
Care co-ordinater
Transition meetings with Elana present

22
Q

What are some forms of SMI (Severe mental illness?)

A

Primary focus on Severe/Serious Mental Illness (SMI)
“Psychological problems that are often so debilitating that their ability to engage in functional and occupational activities is severely impaired”
Commonest disorders - schizophrenia and bipolar disorder, major depressive disorder
Cross-age prevalence ~0.7-0.9%

Drug and alcohol abuse
Dementia/Delirium (not focussed on during this talk, but delirium is a major contributor to morbidity/mortality)

23
Q

What are some physical co-morbidities in SMI?

A

Poor physical health is common

SMI patients are more likely (1.3x for females, 1.2x for males) to have one or more physical health conditions than all patients

Differences more pronounced in younger age groups
Highest health inequality in ages 15-34 for asthma, diabetes, HTN, obesity
SMI patients aged 15-34 are 5x more likely to have 3 or more health conditions

Inequalities persist for obesity, asthma, diabetes, COPD, CHD and stroke after controlling for deprivation, age and sex

24
Q

What is the impact of SMI on mortality?

A

Patients with SMI have a higher premature mortality than the general population

Average reduction in life is 15-20 years in SMI
Schizophrenia – 10-20 years
Bipolar Disorder – 9-20 years
Drug and alcohol use – 9-24 years
Recurrent depression – 7-11 years

Heavy smoking – 8-10 years
Death rate for those under 75years old is 3.7x higher than the general population
Estimated that 2/3 deaths are from preventable physical illnesses

Compared to general population, under 75s with SMI have death rates:
5 times higher for liver disease
4.7 times higher for respiratory disease
3.3 times higher for cardiovascular disease
2 times higher for cancer

Other causes of death include:
Suicide, substance abuse, accidents, dementia, infections

25
Why does SMI have such a big impact on morbidity?
Effects of mental illness Effects of prescribed medication Effects of social circumstance Effects of lifestyle Effects of the healthcare system
26
What are the effects of mental illness on morbidity?
Direct effect of symptoms of mental disorder on physical healthcare Schizophrenia/psychosis Delusional beliefs about physical health Delusions of causes of physical disorders Paranoia/persecutory beliefs about healthcare staff Delusional beliefs around treatments/medications Chronic thought disorder leads to challenging engagement Negative symptoms - Amotivation - Social withdrawal - Cognitive impairment Major Depressive Disorder Amotivation Apathy Beck’s Cognitive Triad (negative thoughts about the world, self and future) Worthlessness/hopelessness/guilt Anxiety Significant social anxiety – not leaving home/secure address Dementia Cognitive impairments lack of concordance with medication Missed appointments
27
What are the effects of prescribed medication on morbidity?
Many psychotropic medications have impacts on physical illness Metabolic Syndrome Type 2 Diabetes Mellitus CVD Bone Mineral Density Loss Renal Disease Thyroid Disease Other miscellaneous disorders
28
What is metabolic syndrome?
Clustering of abnormalities Central obesity Hypertension Dyslipidaemia Glucose Intolerance/Insulin Resistance Hypertension 5-6 fold increase in risk of developing T2DM 3-6 fold increase in risk of mortality due to CVD May be an aetiological factor in some cancers (particularly colon cancer
29
Prevalence of metabolic syndrome
Prevalence in schizophrenia varies in studies, depending on multiple factors (MetS criteria, gender, ethnicity, country, age group, antipsychotic treatment) Prevalence ~19.4 - 68%! Higher prevalence in schizophrenia compared to general population Bipolar disorder prevalence ~ 22-30% Caused/exacerbated by various antipsychotics (particularly atypicals)
30
What can cause obesity/ weight gain in SMI?
Antipsychotics Clozapine/Olanzapine Quetiapine/Risperidone (intermediate risk) Antidepressants Mirtazapine, paroxetine Mood Stabilisers Lithium, Valproate Linked to metabolic syndrome, general poor health Other meds of course linked, but these are common ones
31
T2DM on SMI
Atypical antipsychotics higher risk than typicals Atypical D2 receptor antagonism may have direct effect on development of glucose intolerance (initially via blunted insulin secretory response) Olanzapine/Clozapine highest risk Risperidone intermediate risk Antidepressants may increase risk Likely due to side-effects of increased appetite/sedation/weight gain
32
Bone mineral density loss in SMI
Many antipsychotics lead to raised prolactin levels It is suggested that hyperprolactinaemia leads to BMD loss although studies are contradictory May be more related to lifestyle issues Smoking, reduced physical activity, reduced vitamin D production, alcohol abuse High risk factor for fractures Hip fractures are related to high morbidity/mortality Other fractures may precipitate pain/further loss of mobility and independence
33
What are some msicellaneous drug-related disorders?
Lithium Clinical hypothyroidism (up to 47% of patients!) Renal failure Clozapine Agranulocytosis Myocarditis Chronic severe constipation (spontaneous bowel perforation)
34
What are the effects of social circumstance?
Health generally worse in deprived communities Life expectancy lower in deprived communities Prevalence/Incidence of psychotic disorders 2.5-3.1x higher in most deprived areas compared to least deprived areas Social drift theory Symptoms of SMI/deterioration of cognitive functioning leads to difficulties with functioning and maintenance of living standards Individuals with SMI “drift” into progressively lower socioeconomic bands and/or areas with increased deprivation Social isolation leads to reduced contact with healthcare professionals Reluctance to attend check-ups/health visits Cognitive difficulties Poor interactions with healthcare professionals Detentions under MHA Poor interactions in general health wards/A&E can be related to stigma
35
Effects of lifestyle on co-morbidity in SMI
Smoking! Smoking reducing in general population, but stable in SMI Some studies suggest ~60% of adults with schizophrenia are regular tobacco smokers Poor diet Lack of exercise Amotivation Social isolation Cognitive dysfunction Stigma Drug and alcohol use ~41% dual diagnosis Direct physical illness Liver disease Brain damage (e.g. Wernicke/Korsakoff disease) Accidental overdose Related illness VTE HIV Hepatitis/BBV
36
What are the effects of the healthcare system on morbidity with SMI?
Division of healthcare system and training into silos Psychiatrists focus on mental over physical health De-skilling psychiatrists in physical medicine Poor communication due to separation of physical/mental health wards Completely different sites – RHH/NGH vs MCC/Longley Who is responsible for monitoring of physical health? GPs? Psychiatrists (given number of physical risks of psychotropic meds)? Lower level of healthcare intervention in SMI Lower rates of cardiac stenting or bypass grafting in schizophrenia with CVD People with psychosis are less likely to receive warfarin following CVA SMI patients less likely to receive routine cancer screening Standard of diabetes care is likely to be lower in SMI Related to patient-level effects (as described before) But also… stigma
37
What is diagnostic overshadowing?
Initially in LD patients Assumption that behaviour is due to their learning disability rather without exploring biological determinants Can be extended to SMI/Dementia/Delirium Once a patient has a diagnosis, all new symptoms are assumed to be due to that Woman on AMU with a history of depression, presented with confusion, fever, cough. Medical team referred to psych as she was refusing blood tests and thought confusion must be mental illness, without assessing for delirium/sepsis
38
How can we target health behaviours and MetS (Metabolic syndrome)?
Targeting health behaviours Smoking Poor diet Lack of exercise Targeting signs of Metabolic Syndrome (MetS) Obesity BP Glucose Regulation Blood Lipids
39
Further interventions for SMI
Actively and effectively treat psychiatric illness Appropriate treatment at appropriate dose Proactive treatment of symptoms with aim for functional recovery Active treatment of comorbid substance misuse STOMP/STAMP Stopping overmedication of young people with LD/autism or both Initially an LD/Paediatric initiative, but applicable to adult/OA psychiatry Does this patient really need this medication at this dose? Patient education about risk factors and management of diseases Diabetes courses Healthy heart information Awareness training (this session) and reduction of stigma in healthcare professions ?Review of healthcare systems and how these are organised Reduction in silo-ing and integrated physical/mental healthcare
40