Atrial fibrillation Flashcards
ECG signs of atrial fibrillation (3)
Chaotic baseline
Irregularly irregular QRS complexes
No P-waves
Common secondary causes of AF (4)
Pneumonia
Thyrotoxicosis
Hypertension
Valve disease
What is sick sinus syndrome?
Ischaemia/infarction/fibrosis of the sinus node, presenting with bradycardia and intermittent tachycardia
What are the two “arms” of treatment in AF?
Rate/rhythm control
Anticoagulation
Why do patients with AF often need to anticoagulated?
Turbulent blood flow in the heart increases risk of clot formation, and therefore increases risk of stroke
Options for rate control in atrial fibrillation?
Beta-blockers
Verapamil/diltiazem
Digoxin
Why would amlodipine not be useful for management of AF?
Amlodopine is a dihydropiridine-these have more of an effect on the vasculature rather than the heart
What are the pharmacological effects of digoxin? (2)
Negatively chronotropic- reduces heart rate
Positively inotropic- increases heart contractility
When is digoxin contraindicated?
Patients with second degree/complete heart block
Patients with ventricular arrythmias
What effect does potassium concentration have on digoxin activity?
Low K+ levels increase the effects of digoxin
Why is digoxin dose reduced in renal failure?
Digoxin is renally excreted
Rhythm control options in AF (2)
DC cardioversion
Pharmacological cardioversion
What tool is used to assess stroke risk in AF?
CHADS2VASC
What tool is used to assess the risk of bleeding in patients who are being anticoagulated?
HAS-BLED
What CHADSVASC score should prompt anticoagulation?
2 or above, taking HAS-BLED score into account