Atrial Fibrilation Flashcards

1
Q

What is it?

Who is it more common in?

A

Supraventricular tachyarhythmia

With CHAOTIC and irregular conduction of depolarisation through the atrium and then the ventricles.

Men

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2
Q

Causes by PIRATES:

What does it stand for?

A
Pulmonary 
IHD 
Rheumatic Disease and mitral stenosis 
Alcohol, smoking and caffeine 
Thyrotoxicosis 
Electrolyte abnormalities
Sugar (DM) and Sepsis

Read the following for more info:

Alcohol consumption is a known cause of AFib. In the short term, alcohol disrupts your natural pacemaker, or the electric circuitry in the heart that keeps a normal, steady heartbeat. Disruption of steady electrical signals in the heart can lead to an irregular and fast heartbeat.

Smoking is associated with elevated blood pressure and heart rate which also are risk factors for atrial fibrillation

Drinking too much caffeine could raise your blood pressure and increase your heart rate (which might trigger atrial fibrillation).

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3
Q

Causes by PIRATES:

(P)ulmonary:

  • Why do lung diseases cause AF?
  • List a few? - 5

IHD - list a few? - 3

A

So can high levels of carbon dioxide (CO2) in the blood, a condition common in late-stage COPD. Upper respiratory infections and bronchitis are common in COPD. This can cause the lung’s arteries to narrow or become blocked, a condition called pulmonary hypertension, which can lead to AFib.

PE
Pleural effusion 
COPD 
Lung cancer 
Pneumonia 

Acute MI
HTN
HF

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4
Q

Causes by PIRATES:

Valve stenosis - how does this cause AF?

Electrolyte abnormalities - potassium, magnesium

A

Heart valve stenosis is also linked to a higher risk for atrial fibrillation. For example, mitral valve stenosis results in an obstruction to blood flow from the left atrium to the left ventricle causing the pressure to increase in the left atrium. As a result, the heart enlarges, and atrial fibrillation can occur.

Hypokalaemia

Hypomagnesemia

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5
Q

Classification:

Acute AF

A

Onset within 48 hrs either new or recurrent episode

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6
Q

Classification:

Chronic AF sub-classified as:

  • Paroxysmal AF - what is it?
  • Persistent AF - what it is? - 2
  • Permanent AF
A

Usually self terminates < 7 days

Lasts > 7 days
< 7 days but requires cardioversion - a medical procedure by which an abnormally fast heart rate (tachycardia) or other cardiac arrhythmia is converted to a normal rhythm using electricity or drugs.

Unresolved by cardioversion

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7
Q

Symptoms:

  • What is the patient’s main symptom?
  • Head
  • Lungs
  • What type of pain do they have?
  • 20% will be asymptomatic.

Signs:

  • Pulse
  • BP

Symptoms of complications - 2

A
Palpitations 
Syncope 
SOB 
Angina - central crushing chest pain 
Asymptomatic 

Tachycardia, irregularly irregular and apical pulse may be faster than radial
Hypotension

Stroke/TIA 
Pulmonary oedema (acute HF)
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8
Q

Investigations:

ECG:

What is absent and what replaces it?

What is AF known as if HR>100bpm?

What happens if there is prolonged epodes of this?

What should be used to record if paroxysmal AF suspected? - 2

A

P waves replaced with small irregular F waves

Rapid ventricular response or fast AF

Transient ischaemic changes such as ST-elevation/depression

Event recorders such as loop recorders, Holter monitors etc.

The irregular rhythm in addition to the absence of any clear P waves is typical of atrial fibrillation.

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9
Q

Investigations:

Bloods - why do …?

FBC
U&E
TSH
LFT and coag

A

Anaemia which ay exacerbate HF

Looking for cause

Looking for cause

To check how they will deal with warfarin if they need it

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10
Q

Investigations:

Why do you do a trans-thoracic echo and CXR?

A

Cardiac causes and complications

May show signs of HF

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11
Q

Management:

What are 2 ways to manage AF?

What score is used to determine the risk of a VTE and what score is used to work out the risk of haemorrhage?

A

Rate or rhythm control

CHADVASC score and HASBLED score - they are used in combination

Reducing the risk of thromboembolism especially stroke with chadvasc score > 1 in men and > 2 in women.

If the score 0 for men or 1 for women, then no Rx is given OR just aspirin.

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12
Q

Management:

Drugs to prevent clots

A

Direct oral anticoags (DOAC)

Warfarin

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13
Q

Rate control in AF:

1st line:
Beta-blockers - 2 examples - M, B
Rate-limiting calcium channel blockers - 2 examples

Digoxin is a monotherapy to control the rate. What feature of a patients lifestyle must be present for it to be prescribed?

A

Metoprolol, bisoprolol

Verapamil, diltiazem

They have to be sedentary - so maybe someone who is bed-bound.

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14
Q

Rate control in AF:

2nd line - you combine 2 of the following ………

A

b-blockers, diltiazem (CCB) and/or digoxin

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15
Q

Rate control in AF:

‘Pill in the pocket’ is used in paroxysmal AF. What does this mean?

What other criteria does the patient have to meet to get the above? - 4

What if AF episodes are very infrequent?

A

PRN stall or flecainide (pill in the pocket) - stops the arrhythmia

Infrequent episodes.
Understand how and when to take it.
No structural (LVF, valvular) or ischaemic heart disease.
SBP >100 and HR >70.

No Rx

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16
Q

Rhythm control:

When is this initiated?

Who gets it?

A

If rate control has failed or as an alternative 1st line treatment

New onset AF
AF with reversible causes
AF leading to HF
Patients who it is considered more suitable for (e.g. young patients who are active)

17
Q

Rhythm control:

What is available?

A

Electrical cardioversion

Pharmacological cardioversion

18
Q

Electrical cardioversion:

When is this the preferred choice?

What should be given before starting this to prevent clots?

A

Haemodynamically unstable - SBP<90, syncope, acute HF, MI

THE PERSON IS BASICALLY ON THEIR DEATH BED - YOU SEE THIS IN MOVIES ALL THE TIME!!

Anticoagulation

19
Q

Pharmacological cardioversion:

Indications

How is it administered?

What meds are given if there is no structural heart disease? - 2

What antiarrhythmic drug is given if there are structural or ischaemic HD? - A
Why is this med given through a central line?

What should be given before starting this to prevent clots?

A

Symptoms milder
Situation less urgent

IV - bolus then infusion (maintenance)

flecainide or propafenone

Amiodarone
Risk of thrombophlebitis if done peripherally

Anticoags

20
Q

What drugs should be given if cardioversion is elective?

What is given for long term rhythm control post cardioversion in persistent AF

A

Give thromboprophylaxis 3 wks before
Amiodarone 4 wks pre and up to 12 months post

b-blockers
Dronedarone, amiodarone

21
Q

Catheter ablation:

What is it?
Indications

Methods

A

A minimally invasive procedure
A flexible thin tube (catheter) through the blood vessels to your heart to ablate (stop) abnormal electrical pathways (signals) in the heart tissue.

If refractory or has contraindications to medical therapy
Younger patients to avoid lifetime of meds

Radiofrequency
Cyrotherapy
Microwave

22
Q

What does ablate and pace mean?

When is it considered?

A

Ablation of the AV node followed by pacemaker insertion - can be considered in permanent AF with LV dysfunction.

23
Q

Complications of AF

A

Stroke (5x more likely)
Acute HF and pulmonary oedema
Cardiomyopathy and HF