ATI Chapter 42 - Chemotherapy Agents

Question 1

Antimetabolites

Answer 1

Kill cancer cells by interrupting a specific phase of cell reproduction

Question 2

Antimitotics

Answer 2

Kill cancer cells by inhibiting mitosis and preventing cell division

Question 3

Antitumor antibiotics

Answer 3

Kill cancer cells by stopping the synthesis of rna, dna, or proteins

Question 4

Alkylating agents

Answer 4

Kill fast-growing cancer cells by altering dna structure andpreventing cell reproduction

Question 5

Topoisomerase inhibitors

Answer 5

Kill cancer cells by interrupting dna synthesis

Question 6

Name the Antimetabolite/Antimetabolite

Answer 6

Methotrexate (Rheumatrex, Trexal)

Question 7

Name the Antimetabolite/Pyrimidine

Answer 7

Fluerouracil (Adrucil)

Question 8

S&Sx:
Bone marrow suppression
GI Symptoms (discomfort)

Answer 8

Antimetabolites

Question 9

Able to kill cancer cels only during the S-Phase of the cell cycle

Answer 9

Antimetabolites

Question 10

What are the three subcategories of antimetabolites

Answer 10

Folic Acid Analogs
Pyrimidine Analogs
Purine Analogs