Asthma and Allergies Flashcards
chronic inflamartory disease of the airways with:
- episodic or chronic symptoms of airway obstruction
- bronchial hyperresponsiveness to triggers
- evidence of at least partial reversibility of airway obstruction
- alternative dx have been excluded
asthma
what is the etiology of asthma?
specific cause unknown but it is thought to deal with :
- environmental (allergens, infections, microbes…)
- biologic and genetic risks (immune system)
why is asthma important in kids/
- most common chronic medical condition of childhood, causing significant morbidity
- 6.3 million children have asthma (9%)
which gender is more likely to have asthma?
males
- 80% of asthmatics report onset prior to age 5
- leading cause of hospitalizations
type of asthma that is recurrent wheezing in early childhood, primarily triggered by common viral infections of the respiratory tract
type one
type of asthma that is chronic asthma associated with allergy that persists into late childhood and often adulthood
type 2
what is the pathogenesis of asthma?
- airflow obstruction from bronchoconstriction
- inflammation, edema, and mucus
- production of pro-allergic, pro-inflammatory cytokines
- mediation of inflammatory process by chemokines
triggered activation of MAST cells and histamine degranulation following exposure to allergens (dust, pollen)
extrinsic (allergic) asthma
trigger from tobacco smoke, air polution, strong fumes/odors, chemicals in air, respiratory infections, exercise, cold air, anxiety, stress, GI reflux. aspirin or NSAIDS
intrinsic (non-allergic/idiopathic) asthma
how many asthmatics have both types of triggers?
10%
what are the rescue medications for astmatics?
- short-acting beta agonists (albuterol)
- anticholinergics
*always bring to the appt
what are some comorbidities of asthma?
- allergic rhinitis (hay fever)
- chronic sinusitis
- gastroesophageal reflux disease
- food allergies
- atopic dermatitis, eczema
what causes candadiasis in kids?
immature immune system, antibiotics, steroid inhalers, maternal infection, pacifiers
what are some oral disease prevention with asthmatics?
- drink or rinse with water after inhaler use
- recommend inhaler extenders to dec risk of candadiasis
4% of asthmatics are allergic to NSAIDS, so what should you use instead?
acetaminophen