ASTHMA Flashcards

1
Q

What is asthma?

A

inflammation of the airways

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2
Q

Which form of asthma can be severe and life threatening (acute or chronic)?

A

Acute asthma

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3
Q

How common is asthma?

A

common

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4
Q

What are the risk factors? (10)

A
  1. atopy history
  2. family history of atopy
  3. environment
  4. socio-economic deprivation
  5. obesity
  6. prematurity and low birth weight
  7. viral infections in early childhood
  8. smoking
  9. maternal smoking
  10. early exposure to broad spectrum antibiotics
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5
Q

What causes asthma? (8)

A
  1. cold air
  2. exercise
  3. emotions
  4. allergens - house dust mite, pollen, fur
  5. pets
  6. carpets
  7. feather pillows or duvet
  8. paint sprays
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6
Q

What are the symptoms? (5)

A
  1. intermittent dyspnoea
  2. wheeze
  3. cough
  4. sputum
  5. diurnal variation
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7
Q

What is diurnal variation?

A

a cycle to symptoms - peak flow low in the morning

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8
Q

What are the signs? (6)

A
  1. tachypnoea
  2. wheeze
  3. hyper inflated chest
  4. hyperressonant percussion note
  5. decreased air entry
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9
Q

What types of wheezes are there? (2)

A
  1. audible

2. polyphonic

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10
Q

What are the signs of a severe asthma attack? (4)

A
  1. inability to complete sentences
  2. pulse > 110 bpm
  3. RR> 25 breaths/min
  4. PEF - decreased by 35-50%
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11
Q

What are the signs of a life threatening attack? (6)

A
  1. silent chest
  2. confusion
  3. exhaustion
  4. cyanosis
  5. bradycardia
  6. PEF< 33%
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12
Q

What is the sign of a fatal asthmatic attack?

A

increased PaCO2

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13
Q

What are the differential diagnoses? (8)

A
  1. pulmonary oedema
  2. COPD
  3. large airway obstruction
  4. SVC obstruction
  5. pneumothorax
  6. PE
  7. bronchiectasis
  8. obliterative bronchiolitis
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14
Q

Investigations of an acute asthma attack? (8)

A
  1. PEF
  2. Sputum culture
  3. FBC
  4. U&Es
  5. CRP
  6. blood culture
  7. ABG
  8. CXR
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15
Q

What would the ABG results show in an acute attack of asthma and what is this known as (hypo or hyper-ventilation) ?

A
  • normal/slightly high PaO2
  • low PaCO2
  • hyperventilation
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16
Q

Why is a CXR done in an acute attack of asthma?

A
  • to rule out infection
17
Q

What investigations are done in chronic asthma patients? (5)

A
  1. PEF
  2. spirometry
  3. skin prick test
  4. histamine or methacholine challenge
  5. aspergillus serology
18
Q

What is the drug treatment? (5)

A
  1. short acting beta-2-agonist - salbutamol
  2. inhaled steroid - beclomethasone
  3. long acting beta-2-agonist - salmetarol
  4. leukotriene receptor (if all fails)
  5. oral theophylline (if all fails)
  6. prednisolone (last resort)