Asthma Flashcards
Asthma is 38% higher in who than whites?
Black people
Who has the highest mortality rates from asthma ?
Black women
Asthma effects about how many adult Americans?
20.4 million
Asthma gender differences
Men vs women? (2)
Men are more effected
But women die more too it
We tend not to diganosis asthma in child until 5 years old. Why?
Because children have small airways
Their airways can be obstructed by the smallest things
Reactive airway, they have reactive to a stimuli
After 4-5 years old, they have a pattern. Then we can say that have asthma
How much percentage of people are not using their inhalers correct?
72%
Asthma is the number one reason why kids ?
Miss school
13.8 million miss school
Asthma definition? (2) textbook definition
Combination of bronchial hyper responsive with
reversible expiratory airflow limitation
Asthma definition shorter version or how she says it (2)
Combination of
Bronchial construction ( narrowing )
&
Inflammation
The important part of reversible expiratory airflow limitation, the difference between asthma and COPD is?
Once the construction releases, the airway goes back to normal
Parents think when their kids get asthma they can’t do a lot of things, but you want them to get up and moving ( excerise ) why?
In order to gain resilience
In an adult airway they can handle more ____compared to an infant?
Inflammation
Asthma sign and symptoms may __?
Clinical course can be ___?
Vary
Unpredictable
Clinical course can be unpredictable because everyone Varys but it’s important to make sure the patient has what and why?
Making sure they have medication
In order to prevent an asthma attack
What are the 2 main consequences Of asthma?
Exposure to allergens or irritants triggers the inflammatory cascade involving a variety of inflammatory cells
Inflammation leads to bronchoconstirction, hyperresponsiveness and edema of airways lead to limited airflow
What does a person look like without asthma (3)?
Normal lining
Normal amount of mucus
Muscle relaxes
What does asthma look like in a person? (3)
Swollen lining
Excess amount of mucus
Muscle tightened
When we say more mucus on the asthma it’s usually what color?
Clear
What are some risk factors for asthma and triggers of asthma attacks? (12)
Cockroaches
Second hand smoke
Environmental allergies
Nasals polys
URI
Excersise enduced asthma
Animal dander
Mold
Fire pollution
Occupation
Cold air
Medications
Asthma can also come from where? (5)
GERD - gastroesophacal reflux disease
Asthma triad
Genetics
Immune system
Emotions
Can you just treat the constriction of the asthma? Why?
No because we also need to treat the inflammation if we’re going to reduce risk of death
What is the pathophysiology map for asthma? (10)
Triggers
- infection, allergens, exercise, irritants
Immune activation
- IL-4 & IGE production
Mast cell degranulation
Inflammatory mediators
Vasodilation
- increased capillary permeability
Cellular infiltration
- neutrophils, lymphocytes, eosinophils
Neuropeptides released with autonomic nervous system effects
Bronchospams
Vascular congestion
Etc
Airway remodeling
Bronchial hyperresponsiveness
Airway obstruction
Asthma & ___ & ___?
Allergens
Eczema
IL-4 is a what and functions how?
Cytokine
Functions as a potent regulator of immunity secreted primarily by mast cells