Asthma Flashcards
How can you diagnose asthma?
- Wheeze is suggestive but not pathognomonic
- Response to bronchodilator is suggestive
- Chronic cough may be a primary manifestation
- HISTORY
History taking questions?
- Recurrent cough or wheeze?
- Cold that “go to the chest” or take >10 days?
- Cough/wheeze during a particular time of the year
- Cough/wheeze/SOB when exposed to certain things?
- Used any medications to help you breathe better?
- in the past 12 months - have you had cough, wheeze, or shortness of breath - At night?, Upon awakening?, After play?
- in the past 4 weeks
Common asthma triggers?
- Animals
- Cockroaches/rodents
- Molds/dampness
- Spring (pollen)
- Rainy season (molds)
- Tobacco
- Wood-burning or paraffin stove
- Perfumes, cleaning agents, bug spray
- maize harvesting season
Differential diagnosis for acute wheezing?
- Asthma
- Bronchiolitis
- Atypical infection - causing atypical pneumonia (Myecoplasma)
- Bacterial tracheitis
- Foreign body
- Anaphylaxis - associated with hives, swollen face, stridor and previous reaction to allergen
Causes of recurrent persistent childhood wheeze?
- viral episodic wheeze
- multiple trigger wheeze
- asthma
- tracheo-bronchomalacia
- bronchopulmonary dysplasia
- recurrent anaphylaxis
- cystic fibrosis
- chronic aspiration
- bronchiolitis obliterans
Structural ddx chronic wheezing?
- Tracheo-bronchomalacia
- Vascular rings
- Tracheal stenosis
- Cystic masses
- Tumors or lymphadenopathy
- Cardiac failure
Functional ddx chronic wheezing?
- Asthma
- Gastroesophageal reflux (GERD)
- Recurrent aspiration (e.g CP)
- Cystic fibrosis
- Immunodeficiency
- Bronchopulmonary dysplacia (ex-premie)
- Retained foreign body
- Bronchiolitis obliterans
- Pulmonary oedema
- Vocal cord dysfunction
- Interstitial lung disease
What are the stages of asthma?
- intermittent
- mild persistent
- moderate persistent
- severe persistent
What is intermittent asthma?
Daytime symptoms 2 or fewer days/week
Nocturnal symptoms 2 or fewer nights/month
No interference in daily activities or play
1 or fewer exacerbations per year
What is mild persistent asthma?
Daytime symptoms 3-6 days/week
Nocturnal symptoms 3-4 nights/month
Minor interference with daily activities or play
2 or more exacerbations per year
Effectiveness of SABAs - rescue inhalers?
- Maximum effect after 10-15minutes
- Effective for 2 -4 hours
Use of inhaled corticosteroids (ICS) - preventers?
The most effective prophylactic inhaled therapy
Side effects of ICS?
- impaired growth
- adrenal suppression
- altered bone metabolism
What is moderate persistent asthma?
Daily symptoms
Nocturnal symptoms more than once per week
Daily inhaler use
Some activity limitation
What is severe persistent asthma?
Symptoms throughout the day
Nocturnal symptoms most nights
Significant limitation in activity