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GI2 > associations > Flashcards

associations Flashcards

1
Q

HCV

A

metabolic synd, insulin resistance, NAFLD

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2
Q

Keratocystic odontogenic tumor

A

Gorlin synd (basal cell carcinoma) (mutations on PTCH gene)

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3
Q

Hirschprung’s Dis

A

DS and neuro abns

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4
Q

Peutz-jeghers syndrome

A
  • malignancies to testes, gastric/SI, colon, pancreatic, breast, lung, ovarian and uterine cancers.
  • intussusception
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5
Q

cholelithiasis

A
  • acute cholecystitis.
  • More severe compilcations: empyema, perforation fistulas (from other organs there), inflamm of the biliary tree, obs cholestasis and pancreatitis
  • Increased risk GB carcinoma
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6
Q

cystic fibrosis

A

–>Formation of pancreatic intraductal concretions leads to duct obsts, low grade chronic autodigestion of pancreas, exocrine pancreatic insufficiency

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7
Q

primary sclerosing cholangitis

A

IBD, cholangiocsarcoma

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8
Q

full blown pancreatitis

A
  • systemic inflamm leukocytosis, DIC, edema, ARDS (shock and acute renal tubular necrosis may occur)
  • Peripheral vascular collapse.
  • panc abcess, pseudocyst
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9
Q

campylobacter enterocolitis

A

erythema nodosum

-guillianbarre synd: ascending paralysis

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10
Q

gastric adenoma

A

FAP and chronic gastritis

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11
Q

esophageal mucaosal webs

A
  • GERD, chronic GVH dis, or blistering skin dis’s
  • IF in upper esoph and have Fe-deficiency anemia, glossitis (smooth red inflamm. Of the tongue), koilonchia (spoon-shaped fingernail)and cheilosis (corners of mouth are cracked), may be indicative of Paterson-Brown-Kelly or Plummer-Vinson synd
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12
Q

hepatoblastoma

A

FAP, Beckwith-Wiedemann synd. (WT2 gene abn)

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13
Q

obliterative portal venopathy

A

rheumatologic dis

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14
Q

nodular regenerative hyperplasia –> nodules

A

HIV, AI, portal HTN

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15
Q

panc carcinoma

A

incave spleen, adrenals, colon, stomach, LNs, liver,lungs

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16
Q

Lymphocytic (varioliform) Gastritis

A

-celiac

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17
Q

hemochromatosis

A 
o	Micronodular cirrhosis.
o	DM 
o	Abnormal skin pigmentation
o	Cardiac dysf
--hepatocellular carcinoma
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18
Q

primary biliary cirrhosis

A

hypercholesteremia, and other AIs

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19
Q

salmonella enteritica (typhoid fever)

A

gall stones and the chronic carrier state

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20
Q

α1-antitrypsin deficiency

A

emphysema and hepatic dis, HCC

21
Q

carcinoid tumor

A

endocrine cell hyperplasia, AI chronic atrophic gastritis, MEN-1, and ZE synd

22
Q

juvenille polyps

A

intussusception, intestinal obstruction, or polyp prolapse, colonic adenocarcinoma

23
Q

nonalch fatty liver dis

A 
metabolic synd (w obesity), hepatocellular carcinoma
-contrib ot progression of other liver dis's (HBV, HCV)
24
Q

esophageal varices

A
  • alch cirrhosis

- schistosomiasis

25
Q

hepatic venous outflow obstruction (budd-chiari synd)

A

meloproliferative disorders such as polycythemia vera, inherited disorders of coagulation, antiphospholipid antibody syndrome, paroxysmal nocturnal hemoglobinuria, HCC

26
Q

acute appendicitis

A
  • acute gangrenous appendicitis followed by perforation (suppurative peritonitis)
  • pyelophlebitis, portal v. Thrombosis, liver abscess, bacteremia
27
Q

carcinoid tumor of appendix

A
  • Mucocele – dilated appendix filled w mucin
  • -Represent and obstructed appendix or may be a consequence of mucinous cystadenoma or mucinous cystadenocarcinoma (which wld spread)

-Pseudomyxoma peritonei – when the abdomen fills w tenacious, semisolie mucin

28
Q

granulomatous gastritis

A

Crohn’s, sarcoid and infection (mycobacteria, fungi, CMV, H. Pylori).

29
Q

salmonella enteritidis (salmonellosis)

A

Severe illness more likely in pts with malignancy, immunosuppression, alcoholism, CV dysfunction, sickle cell disease, hemolytic anemia

30
Q

HSV

A

Acute herpetic gingivostomatitis, recurrent herpetic somatitis

31
Q

chronic pancreatitis

A
  • panc indussifiency
  • DM
  • malabs
  • pseudocyst
  • panc canc
32
Q

Eosinophilic esophagitis

A

atopic dermatitis, allergic rhinitis, asthma, peripheral eosinophilia

33
Q

Ménétrier disease

A

gastric adenocarcinoma

34
Q

pigment stones

A

hemo anemias, severe ileal dysf or bypass, bac contamination of biliary tree

35
Q

celiac dis

A
  • dermatitis herpetiformis

- t cell lymphoma (EATL) or small intestinal adenocarcinoma

36
Q

Zollinger-Ellison syndrome

A

MEN1 (Werner synd)

37
Q

apthous ulcer (canker sore)

A

sprue, Celiac’s, inflamm bowel disease, behcet’s disease

38
Q

shigella

A
  • Sterile reactive arthritis, urethritis, conjunctivitis in HLA-B27 (+) males 20-40 yo.
  • Serotype 1 leads to toxin causing hemolytic uremic syndrome
39
Q

GI stromal tumor in children

A

paraganglioma, pulmonary chrondroma (carney triad)

40
Q

peridontitis

A

systemic dis: infective endocarditis, brain abscesses, DS, AIDS, leukemia, Chrons, diab, sarcoidosis, syndromes assoc w neutrophil defect

41
Q

colonic adenocarcinoma

A

metastasis to liver, LNs, lung, bone

42
Q

Fundic gland polyp

A

FAP mutation

43
Q

AI gastritis

A
  • vit B12 deficiency
  • atrophic glossitis
  • megaloblastic anemia (sometimes pernicious anemia)
  • diarrhea
44
Q

pyloric stenosis

A

turners synd, tri18 (edwards synd), erythromycin/azithromycin exposure in the first 2 weeks of life

45
Q

chrons dis

A
  • Extraintestinal: migratory polyarthritis, sacroilitis, ankylosing spondylitis, erythema nodosum, uveitis, cholangitis, amyloidosis, finger clubbing. (same in UC too)
  • Increased risk of adenocarcinoma in pts with longstanding colon involvement.
  • Can lead to obst from strictures
46
Q

Familial adenomatous polyposis

A
  • colorectal adenocarcinoma
  • neoplasia to ampulla of vater, stomach
  • gardner and turcot syndromes
47
Q

EHEC, O157:H7 type

A

HUS, ischemic colitis

48
Q

Hereditary Nonpolyposis Colorectal CAncer (lynch synd)

A

clusters CA at diff sites thru body

GI2 (8 decks)

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