associations Flashcards

1
Q

HCV

A

metabolic synd, insulin resistance, NAFLD

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2
Q

Keratocystic odontogenic tumor

A

Gorlin synd (basal cell carcinoma) (mutations on PTCH gene)

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3
Q

Hirschprung’s Dis

A

DS and neuro abns

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4
Q

Peutz-jeghers syndrome

A
  • malignancies to testes, gastric/SI, colon, pancreatic, breast, lung, ovarian and uterine cancers.
  • intussusception
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5
Q

cholelithiasis

A
  • acute cholecystitis.
  • More severe compilcations: empyema, perforation fistulas (from other organs there), inflamm of the biliary tree, obs cholestasis and pancreatitis
  • Increased risk GB carcinoma
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6
Q

cystic fibrosis

A

–>Formation of pancreatic intraductal concretions leads to duct obsts, low grade chronic autodigestion of pancreas, exocrine pancreatic insufficiency

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7
Q

primary sclerosing cholangitis

A

IBD, cholangiocsarcoma

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8
Q

full blown pancreatitis

A
  • systemic inflamm leukocytosis, DIC, edema, ARDS (shock and acute renal tubular necrosis may occur)
  • Peripheral vascular collapse.
  • panc abcess, pseudocyst
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9
Q

campylobacter enterocolitis

A

erythema nodosum

-guillianbarre synd: ascending paralysis

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10
Q

gastric adenoma

A

FAP and chronic gastritis

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11
Q

esophageal mucaosal webs

A
  • GERD, chronic GVH dis, or blistering skin dis’s
  • IF in upper esoph and have Fe-deficiency anemia, glossitis (smooth red inflamm. Of the tongue), koilonchia (spoon-shaped fingernail)and cheilosis (corners of mouth are cracked), may be indicative of Paterson-Brown-Kelly or Plummer-Vinson synd
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12
Q

hepatoblastoma

A

FAP, Beckwith-Wiedemann synd. (WT2 gene abn)

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13
Q

obliterative portal venopathy

A

rheumatologic dis

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14
Q

nodular regenerative hyperplasia –> nodules

A

HIV, AI, portal HTN

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15
Q

panc carcinoma

A

incave spleen, adrenals, colon, stomach, LNs, liver,lungs

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16
Q

Lymphocytic (varioliform) Gastritis

A

-celiac

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17
Q

hemochromatosis

A
o	Micronodular cirrhosis.
o	DM 
o	Abnormal skin pigmentation
o	Cardiac dysf
--hepatocellular carcinoma
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18
Q

primary biliary cirrhosis

A

hypercholesteremia, and other AIs

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19
Q

salmonella enteritica (typhoid fever)

A

gall stones and the chronic carrier state

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20
Q

α1-antitrypsin deficiency

A

emphysema and hepatic dis, HCC

21
Q

carcinoid tumor

A

endocrine cell hyperplasia, AI chronic atrophic gastritis, MEN-1, and ZE synd

22
Q

juvenille polyps

A

intussusception, intestinal obstruction, or polyp prolapse, colonic adenocarcinoma

23
Q

nonalch fatty liver dis

A
metabolic synd (w obesity), hepatocellular carcinoma
-contrib ot progression of other liver dis's (HBV, HCV)
24
Q

esophageal varices

A
  • alch cirrhosis

- schistosomiasis

25
hepatic venous outflow obstruction (budd-chiari synd)
meloproliferative disorders such as polycythemia vera, inherited disorders of coagulation, antiphospholipid antibody syndrome, paroxysmal nocturnal hemoglobinuria, HCC
26
acute appendicitis
- acute gangrenous appendicitis followed by perforation (suppurative peritonitis) - pyelophlebitis, portal v. Thrombosis, liver abscess, bacteremia
27
carcinoid tumor of appendix
- Mucocele – dilated appendix filled w mucin - -Represent and obstructed appendix or may be a consequence of mucinous cystadenoma or mucinous cystadenocarcinoma (which wld spread) -Pseudomyxoma peritonei – when the abdomen fills w tenacious, semisolie mucin
28
granulomatous gastritis
Crohn’s, sarcoid and infection (mycobacteria, fungi, CMV, H. Pylori).
29
salmonella enteritidis (salmonellosis)
Severe illness more likely in pts with malignancy, immunosuppression, alcoholism, CV dysfunction, sickle cell disease, hemolytic anemia
30
HSV
Acute herpetic gingivostomatitis, recurrent herpetic somatitis
31
chronic pancreatitis
- panc indussifiency - DM - malabs - pseudocyst - panc canc
32
Eosinophilic esophagitis
atopic dermatitis, allergic rhinitis, asthma, peripheral eosinophilia
33
Ménétrier disease
gastric adenocarcinoma
34
pigment stones
hemo anemias, severe ileal dysf or bypass, bac contamination of biliary tree
35
celiac dis
- dermatitis herpetiformis | - t cell lymphoma (EATL) or small intestinal adenocarcinoma
36
Zollinger-Ellison syndrome
MEN1 (Werner synd)
37
apthous ulcer (canker sore)
sprue, Celiac’s, inflamm bowel disease, behcet's disease
38
shigella
- Sterile reactive arthritis, urethritis, conjunctivitis in HLA-B27 (+) males 20-40 yo. - Serotype 1 leads to toxin causing hemolytic uremic syndrome
39
GI stromal tumor in children
paraganglioma, pulmonary chrondroma (carney triad)
40
peridontitis
systemic dis: infective endocarditis, brain abscesses, DS, AIDS, leukemia, Chrons, diab, sarcoidosis, syndromes assoc w neutrophil defect
41
colonic adenocarcinoma
metastasis to liver, LNs, lung, bone
42
Fundic gland polyp
FAP mutation
43
AI gastritis
- vit B12 deficiency - atrophic glossitis - megaloblastic anemia (sometimes pernicious anemia) - diarrhea
44
pyloric stenosis
turners synd, tri18 (edwards synd), erythromycin/azithromycin exposure in the first 2 weeks of life
45
chrons dis
- Extraintestinal: migratory polyarthritis, sacroilitis, ankylosing spondylitis, erythema nodosum, uveitis, cholangitis, amyloidosis, finger clubbing. (same in UC too) - Increased risk of adenocarcinoma in pts with longstanding colon involvement. - Can lead to obst from strictures
46
Familial adenomatous polyposis
- colorectal adenocarcinoma - neoplasia to ampulla of vater, stomach - gardner and turcot syndromes
47
EHEC, O157:H7 type
HUS, ischemic colitis
48
Hereditary Nonpolyposis Colorectal CAncer (lynch synd)
clusters CA at diff sites thru body