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Neuro > Ascending pathways of spinal cord > Flashcards

Ascending pathways of spinal cord Flashcards

1
Q

3 diff categories of ascendin info carried by spinal cord

A

discriminatory - determines type/location/intensity of stimulus
reflexive - activates responses to create behavioral state change with appropriate stereotyped motor responses
Postural - informs or joint, tendon, and muscle position at unconscious level

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2
Q

discriminatory

A 
•Dorsal columns/medial lemniscus (DCML)
–Fasciculus gracilis
–Fasciculus cuneatus
•Anterolateral system
–Neospinothalamic
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3
Q

reflexive

A

•Anterolateral system
–Paleospinothalamic
–[Spinoreticular]
–[Spinomesencephalic

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4
Q

postural

A 
•Spinocerebellartracts
–Cuneocerebellar
–[Rostral spinocerebellar]
–Dorsal spinocerebellar
–Ventral spinocerebellar
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5
Q

faster, wider axons

A

travel to white matter in posterior funuliculi, mechanoreception and tactile, type I and II

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6
Q

slower, thin axon

A

travel to lamina I to VI in dorsal horn, nociceptive (nociceptors, themoreceptors, mechanoreceptors, and visceral afferents, Adelta and C

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7
Q

discriminatory pathway are how many neurons long

A

3

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8
Q

postural pathways are how many neurons long

A

2

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9
Q

discriminatory or non-discriminatory decussates?

A

discriminatory (pinpointing goes to other side, non-pinpointing does not)

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10
Q

Dorsal Columns also called the

A 
posterior columns
medial lemniscus (when in medulla)
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11
Q

dorsal columns type of info

A

tactile discrimination and conscious prorioception

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12
Q

dorsal columns point of origin

A 
meissners corpuscle
merkesl disks
pacinian corpuscles
ruffinis ending in skin muscle spindles
Golgi tendon organs in muscles joints and tendons
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13
Q

dorsal columns cell bodies

A

dorsal root ganglion

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14
Q

dorsal columns first synapse

A

nucleus cuneatus or gracilis in caudal medulla

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15
Q

dorsal columns enters spinal cord

A

medial aspect of dorsal horn, fasciculus cuneatus or gracilis

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16
Q

dorsal columns decussates

A

internal arcuate fibers ventral to cuneatus and gracilis (becomes medial lemniscus)

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17
Q

dorsal columns second synapse

A

ventral posteriolateral nucleus (VPL) or thalamus

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18
Q

dorsal columns final destination

A

primary somatosensory cortex (via internal capsule and corona radiata

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19
Q

where is posterior intermediate sulcus located

A

thoracic and higher

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20
Q

gracilis is for

A

lower part of body, lumbar and sacral, nuclei separated by posteiro intermediate septum

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21
Q

cuneatus is for

A

upper part of body, thoracic and cervical

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22
Q

cuneatus in lumbar

A

no

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23
Q

how is information organized in posterior columns

A

lumbar has no posterior intermediate sulcus, info is organized from medial to lateral with medial being lower in body

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24
Q

intermediate sulcus does what

A

divides gracilis and cuneatus

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25
Q

in medulla fasciculi change to

A

nuclei

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26
Q

tactile nociceptive and conscious proprioceptive infor are represented where

A

primary somatosensory cortex

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27
Q

dorsal columns internal arcuate fasciculus

A

arching fibers

settle at the medial lemniscus

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28
Q

Anterolateral system neospinothalamic is called the

A

neospinothalamic tract

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29
Q

Anterolateral system type

A

pain, temp and poorly localized touch

30
Q

Anterolateral system neospinothalamic point of origin and receptors

A

free nerve endings (TRP Vchannels) in skin viscera and muscles

31
Q

Anterolateral system neospinothalamic primary cells bodies

A

dorsal root ganglion

32
Q

Anterolateral system neospinothalamic first synapse

A

Lamina I-VI

33
Q

Anterolateral system neospinothalamic enters spinal cord and travels

A

dorsal horn (Lissauer’s Fassciculusto ascend at least 1 segment), after 1stsynapse, travels through anterior white commissure, ascends through anterolateral spinothalamictract

34
Q

anterolateral system neospinothalamic decussates

A

spinal cord after first synapse

35
Q

anterolateral system neospinothalamic second synapse

A

ventral posteriolateral nucleus (VPL) of thalamus

36
Q

anterolateral system neospinothalamicfinal desination

A

primary somatosensory cortex (via internal capsule and corona radiate)

37
Q

anterolaterl system neospinothalamic organized in spinothalmic tract

A

CTLS from mdial to posterior

38
Q

anterolateral system neospinothalamic tidbits

A

2nd order neuron is highly myelinated

in midbrain anterolateral and medial lemniscus kindof merge so you get pain and tactile in same place

39
Q

Anterolateral system Paleospinothalamic tract type of info

A

poorly localized pain, fibromyalgia

40
Q

Anterolateral system Paleospinothalamic tract point of origin and receptors

A

Free nerve endings (TRP channels) in skin, viscera, muscles

41
Q

Anterolateral system Paleospinothalamic tract primary cell bodies

A

dorsal root ganglion

42
Q

Anterolateral system Paleospinothalamic tract first synapse

A

Lamina I-VI

43
Q

Anterolateral system Paleospinothalamic tract enters spinal cord and travels

A

dorsal horn (Lissauer’s Fassciculusto ascend at least 1 segment), after 1stsynapse, travels bilaterally, ascends through anterolateral spinothalamictract

44
Q

Anterolateral system Paleospinothalamic tract decusstes

A

spinal cord after 1st synapse

45
Q

Anterolateral system Paleospinothalamic tract second synapse

A

intralaminar nuclei of thalamus

46
Q

Anterolateral system Paleospinothalamic tract final destination

A

bilateral cortex, poorly localized (includes cingulate gyrus and insula (both in limbic lobe, have bad feeling with fibromyalgia))

47
Q

syrinx in spinal cord

A

get syringomyelia, a problem with horns which usually aren’t affected bc ther are interior, but fluid filled sac is pressing on them

48
Q

4 tracts that make up prorioception

A
  • Dorsal spinocerebellar - lower fine component of prorpioception
  • Ventral spinocerebellar - lower whole limby prioprioception
  • Rostral spinocerebellar(?) - upper limb prioprioception (don’t worry about)
  • Cuneocerebellar - upper limb fine prioprioception
49
Q

Dorsal Spinocerebellar and cunocerebellar type of info

A

unconscious proprioception

50
Q

Dorsal Spinocerebellar and cunocerebellar point of origin and receptors

A

muscle spindles, Golgi tendon in muscle joint and tendons

51
Q

Dorsal Spinocerebellar and cunocerebellar cell bodies

A

DRG

52
Q

Dorsal Spinocerebellar and cunocerebellar 1st synapse

A

Clarke’s Nucleus (aka nucleus dorsalis) of thoracic cord if dorsal spinocerebellar. Accessory cuneatenucleus in caudal medullaif cuneocerebellar

53
Q

Dorsal Spinocerebellar and cunocerebellar enters spinal cord and travels

A

posterior funiculi (thickens with dorsal columns)

54
Q

Dorsal Spinocerebellar and cunocerebellar decussates

A

none

55
Q

Dorsal Spinocerebellar and cunocerebellar second synapse

A

vermis/paravermis of the cerebellum via inferior cerebellar peduncle

56
Q

dorsal spinocerebellar and cuneocerebellar final destination

A

deep cerebellar nuclei (via purkinje cells)

57
Q

Dorsal spinocerebellar overview

A

hitchhikes on fasciculus gracilis until l3 then it is visible as dorsal spinocerebellar tract

not visible until l3

58
Q

cuneocerebellar

A

hitchhikes on fasciculus cuneatus

59
Q

clarkes nucleus

A

DORSAL SPINOCEREBELLAR
•When below C8, unconscious proprioceptiveinfo hitchhikes on posterior column.
–Synapses in Lamina VII
–Visible L3 to C8
•CLARKE’S COLUMN/CLARKE’S NUCLEUS/NUCLEUS DORSALIS

60
Q

cuneocerebellar above C8

A

•When above C8, synapses in accessory/external/lateral cuneate nucleus
–Caudal Medulla

61
Q

which sense is ipsilaterla, contralateral and bilateral

A

ipsi - proprioception
contra-discriminatory
bilat-reflexes

62
Q

Dorsal Spinocerebellar and cunocerebellar in cerebellum

A

intracerebellar pathway

enter through peduncle and are changed to mossy fibers

mossy fibers synapes on granule cells
creating second synapse in the system

granule cell axons go to superior surface and bifurcate and then are called parallel fibers which then synapse on purkinje cells

purkinje cells take axon signal to dcn (deep cerebellar nuclei)

last one is 5th order neuron

63
Q

Ventral spinocerebellar type o info

A

unconscious proprioception

64
Q

Ventral spinocerebellar point of origin and receptors involved

A

muscle spindle, Golgi tendon organ in muscle joint and tendon

65
Q

Ventral spinocerebellar cell bodies

A

drg

66
Q

Ventral spinocerebellar first synapse

A

lamina VII then travels to posterior funiculi

67
Q

Ventral spinocerebellar decussates

A

immediately in spinal cord

68
Q

Ventral spinocerebellar second synapse

A

vermis/paravermisof the cerebellum via superiorcerebellar peduncle. Will then decussate again!

69
Q

Ventral spinocerebellar final destination

A

deep cerebellar nuclei (via purkinje cells)

70
Q

Ventral spinocerebellar hitchkies

A

hitchhikes on fasciculus gracilis until clarkes nucleus appears (synapes right next to it in lamina VII)

Neuro (10 decks)

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