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Micropara Finals > Arthropod Borne Viruses > Flashcards

Arthropod Borne Viruses Flashcards

1
Q

Arboviruses

A

Bunyaviridae
Flaviviridae
Reoviridae
Togaviridae

Transmitted by bloodsucking arthropods
Vector acquires a lifelong infection through ingestion of blood from a viremic vertebrate

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2
Q

Bunyaviridae
Genus orthobunyavirus

A

California encephalitis
Guama
La crosse
Oropouche
Turlock viruses
-mosquitos

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3
Q

Genus hantavirus

A

Hantaan virus (korean hemorrhagic fever)
Seoul virus

Rodent borne

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4
Q

Genus nairovirus

A

Crimean congo hemorrhagic fever
Ticks

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5
Q

Genus phlebovirus

A

Heartland virus

Mosquitos
Ticks
Sandflies

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6
Q

Flaviviridae

A

Initially under togaviridae group b arbovirus

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7
Q

Genus flavivirus

A

Brazilian encephalitis (rocio virus)
Yellow fever, zika

Mosquitos
Ticks

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8
Q

Genus coltivirus

A

Colorado tick fever
Ticks
Mosquitos

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9
Q

Genus orbivirus

A

African horse sickness
Bluetongue virus
Mosquitos

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10
Q

Genus alphavirus

A

Chikungunya
Eastern, western, Venezuelan equine

Mosquitos

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11
Q

Fevers of undifferentiated type +/-

A

Macopopopular rash, usually benign

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12
Q

Encephalitis (inflammation of the brain)

A

Often with a high case of fatality

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13
Q

Hemorrhagic fevers

A

Also frequently severe & fatal

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14
Q

Chikungunya

A

Vector: aedes aegypti, albopictus

Resemble dengue

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15
Q

Zika virus

A

Vector aedes egypti

In utero infection: Microcephaly

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16
Q

Rift valley fever

A

Phlebovirus from bunyaviridae

Vector: Aedes sp

17
Q

Papataci fever

A

aka sandfly fever, phlebotomus fever

18
Q

Severe fever with theombocypenia syndrome

A

Phlebovirus from bunyaviridae
Tick

19
Q

Heartland virus

A

Phlebovirus from bunyaviridae
Vector: amblyomma americanum (lone star tick)

20
Q

Colorado tick fever

A

aka mountain fever, tick fever
Vector: demacentor andersoni (wood tick)

21
Q

Hemorrhagic fevers

A

Dengue fever
Yellow fever

22
Q

Yellow fever

A

Yellow fever virus
Aedes aegypti

Hepatorenal failure 15%

Live attenuated vaccine

23
Q

Dengue fever

A

aka breakbone fever
Aedes aegypti, aedes albopictus (daytime biters)

4 serotypes

Findings:
Febrile phase- saddleback or biphasic fever
Critical phase- rapid decline of platelet count
Defervescence- fever
decreases, hemorrhagic if
untreated
Recovery phase- bradycardia

24
Q

Dengue hemorrhagic fever

A

Mostly in persons with 2nd dengue infection

25
Q

Dengue shock syndrome

A

Severe case of dengue hemorrhagic fever
A protein losing shock syndrome

26
Q

Dengue classification

A

Dengue without warning signs
Dengue with warning signs
Severe dengue fever

27
Q

Dengue diagnosis

A

Acute phase: 0-7 days
NAAT (RT-PCR) + IgM OR
Non structural protein 1 (ns1) elisa + IgM
Convalescent phase: >7days
IgM

28
Q

Dengvaxia vaccine

A

Tetravalent live attenuated vaccine
9-16 yo
3 doses, 6mos apart

29
Q

Encephalitis

A

Incubation 4-21 days

30
Q

Rodent borne viruses

A

Cause hemorrhagic fever
Contact with body fluids or secretions

Hemorrhagic fever with renal syndrome
Lassa fever
South american hemorrhagic fever
African hemorrhagic fever

31
Q

Hemorrhagic fever with renal syndrome
HFRS

A

Hantavirus
Peorsmyscus manicultaus (deer mouse)

32
Q

Hantavirus pulmonary syndrome

A

Not a hemorrhagic fever

33
Q

Lassa & luno fever

A

Lassa virus and lujo virus - arenaviridae
Mastomy natalensis (lassa)

Deafness- common complication

34
Q

South american hemorrhagic fever

A

Bleeding is more common than in lassa fever

35
Q

African hemorrhagic fever

A

Marburg & ebola virus from filoviridae
Highly virulent in human & nonhuman primates

Often leading to shock & death

36
Q

Filoviridae

A

Long & threadlike
Require maximum conditions
Biosafety level 4

37
Q

Ebolavirus

A

Caused recurrent outbreaks
Largwst known outbreak:
Western africa, 2014-2016
>28k cases 11k deaths

Micropara Finals (10 decks)

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