Arthropathie Microcristalline Flashcards

1
Q

Éthologie goutte secondaire

A

Irc
Médicaments (dt, furosemide,acetazolamide, ciclosporinr, tacrolimus )
Enzymopathie (déficit hypoxanyine bien une phosphoribosyl transferase)
Possible génétique

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2
Q

Contre indication colchicine

A

Association avec

  • macrolide
  • pristinamycine
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3
Q

Traitement accès goutte

A

Colchicine

+/- ains si intolérance colchicine ou ci

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4
Q

Effets indésirables colchicine

A

Digestifs (diarrhées)
Cutanés
Hémato (neutropenie / thrombopénie / pancytopenie)
Musculaire

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5
Q

Aspect cristaux ppc

A

Parallélépipèdique

Peu réfringent

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6
Q

Étiologies secondaires chondrocalcinose

A

Hemochromatose
Hypomagnesemie
Hyperpth

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7
Q

EI allopurinol

A

Réaction allergique (toxidermies)

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8
Q

EI febuxostat

A

Troubles digestifs
Céphalées
Anomalies hépatiques
Allergies cutanées

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9
Q

CI FEBUXOSTAT

A

ICC
Cardiopathie ischémique
Azathioprine
Mercaptopurine

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10
Q

Localisations dépôts phosphate de ca (apatite)

A

Structures péri articulaire

  • tendons
  • bourses sereuses
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