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Systems Path 1 > Arthritis > Flashcards

Arthritis Flashcards

1
Q

Arthritis

A

Inflammation of joint

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2
Q

Types of arthritis

A
  1. Degenerative
  2. Immune mediated
  3. Metabolic
  4. Infectious
  5. Neoplastic
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3
Q

___ major source of morbidity

A

Osteoarthritis

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4
Q

Types of osteoarthritis

A

OA

DJD

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5
Q

MC joint disorder

A

Osteoarthritis

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6
Q

Advanced osteoarthritis can cause

A

Inflammation and subchondral changes

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7
Q

___ have limited growth capacity

A

Chondroctyes

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8
Q

MC form OA

A

Primary

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9
Q

Secondary OA due to

A

Previous injury or deformity

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10
Q

Common locations for OA

A

Cervical and lumbar spine
DIP joints
1st MCP joint
1st TMT joint

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11
Q

Least likely to cause ankylosis

A

OA

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12
Q

____ Patients have clinically significant inflammation

A

50%

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13
Q

____ and ____ seen with advanced OA

A

Inflammation

Subchondral cyst

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14
Q

Joint mice

A

Free fragment of bone causing pain

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15
Q

Risk factors for OA

A 
>50 yo
Genetics
Estrogen
High bone density 
Mechanical stress
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16
Q

Osteophytes ____ impinge nerve roots

A

Rarely

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17
Q

____ at DIP joints observed in OA

A

Heberden’s nodes

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18
Q

RA is ___ Disease and is chronic and ___

A

Autoimmune

Systemic

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19
Q

___ present in 80% RA cases

A

Rheumatoid factor

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20
Q

___ present in 70% RA

A

Anti-cyclic citrullinated peptides

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21
Q

Signs of RA

A 
Weakness
Malaise 
Fever
Decrease ROM
Cachexia
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22
Q

RA MC affects

A

Small joints

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23
Q

____ observed in 30% of RA

A

Atlanto-axial instability

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24
Q

Pannus in RA can cause

A

Ulnar deviation

Swan-neck deformity

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25
Q

Age for RA

A

Age 35-50

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26
Q

Sex more likely to get RA

A

Females 3-5X

27
Q

Felty Syndrome combo of

A

RA
Neutropenia
Splenomegaly

28
Q

Felty Syndrome MC in

A

Elderly females

29
Q

Caplan Syndrome combo of

A

RA

Pneumoconiosis

30
Q

Caplan Syndrome can mimic

A

Asthma

31
Q

Juvenile RA

A

Autoimmunity of mult tissues

32
Q

Juvenile RA affects what part of body

A

Large joints

Knee, hip

33
Q

JRA MC in

A

Females

34
Q

Biphasic age of JRA

A

MC 1-3 yo

6-13 yo

35
Q

Still’s disease

A

JRA + spiking fever, rash, pericarditis

36
Q

JRA is ___ for RF

A

Negative

37
Q

Scheuermann’s Disease aka

A

Juvenile kyphosis

38
Q

Diagnosis for scheuermann’s Disease

A

Wedge shaped vertebrae

> 3 consecutive
5 degree angle

39
Q

Scheuermann’s Disease MC in

A

Adolescent males

40
Q

Symptoms of scheuermann’s

A

Excesses T kyphosis
Schmorl’s nodes (end plate herniation up into vertebral body)
Aching pain worse with activity

41
Q

Seronegative spondyloarthropathies

A

Autoimmune attack (PEAR)

42
Q

PEAR

A

Psoriatic arthritis
Enteropathic arthritis
Ankylosing spondylitis
Reactive arthritis

43
Q

Enterophathic arthritis associated with

A

Crohn’s

UC

44
Q

Ankylosing spondylitis associated with

A

Inflammation
Sacroiliitis
Syndesmophytes
Ankylosis of SI joint

45
Q

AS MC in

A

Males

46
Q

Radiographic findings associated with advanced Ankylosing spondylitis

A 
Syndesmophytes 
Bamboo spine 
Trolly track sign 
Ankylosis of SI joint 
Ankylosis of L spine 
Dagger sign 
Hypolordosis of L spine
Squaring of V bodies
47
Q

Rhyme for reactive arthritis

A

Can’t see
Can’t pee
Can’t climb tree

48
Q

Can’t see for Reactive arthritis refers to

A

Conjunctivitis

Uveitis

49
Q

Can’t pee of reactive arthritis refers to

A

Urethritis
Cervicitis
Diarrhea

50
Q

Can’t climb tree of reactive arthritis refers to

A

Arthritis in large joints (esp Achilles’ tendon)

51
Q

Reactive arthritis is ____ and associated with ____

A

Autoimmune

Infection

52
Q

Infections that can trigger reactive arthritis

A

GI: salmonella, shigella

GU: gonorrhea, chlamydia

53
Q

Reactive arthritis MC in

A

Males 20-40

54
Q

Polymyalgia rheumatica (PMR) aka

A

Idiopathic chronic inflammation

55
Q

Symptoms of PMR

A

Prolonged morning stiffness
Shoulder pain
Hip pain

56
Q

PMR MC in

A

Females
> 50 yo
Northern Europeans

57
Q

PMR associated with

A

Giant cell arteritis

58
Q

Treatment for PMR

A

Corticosteroids

59
Q

Primary gout

A

Abnormal purine metabolism

MC

60
Q

Secondary gout

A

After disease or medication

61
Q

Chronic topheaceous gout

A 
Erosion of joint and loss of joint space 
Gouty nephropathy (20% lethal)
62
Q

Symptoms of gout

A

Tissues red, swollen, warm, painful

63
Q

Gout MC to affect

A

MTP joint of Hallux

64
Q

Gout involves _____ accumulating

A

Uric acid/ monosodium urate crystals

Systems Path 1 (12 decks)

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