Arterial.6.Buerger's disease Flashcards
Definition of Buerger’s disease
It is a clinical syndrome of severe chronic inflammation of the entire neurovascular bundle of the small blood vessels of L.L & hands.
Alternative name for Buerger’s disease
thrombo-angitis obliterans
ETIOLOGY of Buerger’s disease
The etiology is unknown.
The disease occurs exclusively in smokers, it may represent an allergic response nicotine.
Gender affected in Buerger’s disease
Buerger’s disease affects males only.
Difference between Atherosclerosis and Buerger’s disease
- Age of start
- Gender
- Etiology
- Level of lesion
Age of start of Atherosclerosis in Difference between Atherosclerosis and Buerger’s disease
Elderly
Age of start of Buerger disease in Difference between Atherosclerosis and Buerger’s disease
20-40 years
Gender of Atherosclerosis in Difference between Atherosclerosis and Buerger’s disease
Commoner in males
Gender of Buerger disease in Difference between Atherosclerosis and Buerger’s disease
Exclusively in males
Etiology of Atherosclerosis in Difference between Atherosclerosis and Buerger’s disease
Main risk factors are
- Hypertension
- High cholesterol
- DM.
Etiology of Buerger disease in Difference between Atherosclerosis and Buerger’s disease
Excessive smoking
Level of lesion in Atherosclerosis in Difference between Atherosclerosis and Buerger’s disease
Aorto-iliac
or
Femoro-popliteal
Level of lesion in Buerger disease in Difference between Atherosclerosis and Buerger’s disease
Distal vessels with patchy distribution
CLINICAL PICTURE of Buerger’s disease
As chronic L.L ischemia of Atherosclerosis with the following differences:
The disease is suspected When a young male who is heavy smoker complains of chronic ischaemia in one or more limbs
Rest pain is an early feature & trophic changes are common
The disease may be accompanied by migrating thrombophlebitis and 2ry v.v.
Raynaud’s phenomenon may be superimposed.
Investigations of Buerger’s disease
Arteriography is rarely necessary to confirm the diagnosis.