Arterial Disorders Flashcards
inflammation of vessel wall
vasculitis
presents as fever, malaise, GI issues, myalgia/arthralgia
vasculitis
immune mediated and due to infections
vasculitis
this is due to fibromuscular dysplasia
renal artery stenosis
increased bp due to this; beaded appearance
renal artery stenosis
vasculitis of aorta and branches of extremities, head and neck
large vessel
vasculitis of visceral arteries and branches
medium vessel
vasculitis of arterioles, venules, capillaries
small vessel
giant cell (temporal) arteritis
Takayasu arteritis
large vessel vasculitis
polyarteritis nodosa
Kawasaki disease
medium vessel vasculitis
wegener granulomatosis
Churg-Strauss syndrome
Microscopic polyangiitis
small vessel vasculitis
due to drug hypersensitivity or viral infection
immune complex deposition
drug that forms immune complexes and deposit in large vessel
penicillin
30% of patients w/ polyarteritis nodosa are ____
Hep B +
autoantibodies directed against enzymes of neutrophils
ANCAs
targeted antigen is PR3 of neutrophils; cytoplasmic
c-ANCA
targeted MPO; perinuclear
p-ANCA
c-ANCA
p-ANCA
most common large vessel vasculitis
Giant-Cell (Temporal) Arteritis
granulomatous inflammation; facial pain, HA, painful chewing, diplopia/vision loss
Giant Cell (Temporal) Arteritis
granulomatous vasculitis seen in women <40 yrs
Takayasu Arteritis
reduced bp and weaker pulses in upper extremities; coldness/numbness in fingers
Takayasu arteritis